Description

3-Bromo-2,4,5,6-Tetrafluorobenzotrifluoride is a highly fluorinated aromatic building block of significant interest in advanced organic synthesis. This compound matters for its role as a key precursor in the development of pharmaceuticals, agrochemicals, and specialty materials, where its unique halogen and fluorine substitution pattern enables precise molecular modifications. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and electronic chemicals industries seeking to introduce specific fluorinated motifs into complex molecules.

Application

• Pharmaceutical Intermediate: Serves as a critical building block for the synthesis of fluorinated active pharmaceutical ingredients (APIs), particularly in oncology and CNS drug candidates.
• Agrochemical Synthesis: Used in the development of next-generation herbicides, fungicides, and insecticides, where fluorine atoms enhance biological activity and environmental stability.
• Liquid Crystal & OLED Materials: Acts as a precursor for fluorinated components in electronic display materials, improving dielectric anisotropy and thermal stability.
• Polymer & Resin Modification: Incorporated into specialty polymers to impart unique surface properties, chemical resistance, and low refractive index.
• Organic Synthesis Reagent: Employed in cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig) and nucleophilic aromatic substitution due to the reactivity of the bromine and fluorine substituents.
• Fluorinated Surfactant & Coating Precursor: Used to synthesize surface-active agents and high-performance coatings with oil- and water-repellent characteristics.

Basic Information

Product Name	3-Bromo-2,4,5,6-Tetrafluorobenzotrifluoride
CAS No.	113601-46-0
Molecular Formula	C7BrF7
Molecular Weight	288.97 g/mol
Synonyms	1-Bromo-2,3,5,6-tetrafluoro-4-(trifluoromethyl)benzene; 3-Bromo-2,4,5,6-tetrafluoro-α,α,α-trifluorotoluene; Benzene, 1-bromo-2,3,5,6-tetrafluoro-4-(trifluoromethyl)-; 2,3,5,6-Tetrafluoro-4-(trifluoromethyl)bromobenzene; α,α,α,2,3,5,6-Heptafluoro-4-bromotoluene; 4-Bromo-2,3,5,6-tetrafluorobenzotrifluoride; Heptafluorobromotoluene (specific isomer); Pentafluorobenzotrifluoride, 3-bromo- derivative
EINECS	Contact for details

Quality Control

Our 3-Bromo-2,4,5,6-Tetrafluorobenzotrifluoride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including GC, HPLC, and NMR, to ensure high chemical purity and consistent performance. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are available upon request. We support development and commercial projects requiring material that meets stringent internal specifications aligned with cGMP and ISO 9001 principles.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, well-ventilated place, ideally at controlled room temperature (15-25°C). Due to its highly volatile nature, ensure containers are securely sealed and stored upright. Keep away from heat, sparks, and open flames. Incompatible with strong bases and reactive metals.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC)	≥ 98.0%
Water Content (KF)	≤ 0.1%
Related Substances (GC)	Individual impurity ≤ 0.5%, Total impurities ≤ 2.0%
Density (20°C)	~1.9 g/mL
Boiling Point	~150-155°C

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.