Description

Pd 125,530, trans-(±)-3,4,4A,10B-Tetrahydro-4-Propyl-2H,5H-[1]Benzopyrano[4,3-B]-1,4-Oxazin-9-Ol Hydrochloride is a high-purity, complex heterocyclic compound primarily utilized as a critical intermediate or reference standard in advanced pharmaceutical research and development. Its value lies in its specific stereochemistry and functional groups, which make it a key building block for synthesizing novel therapeutic agents targeting the central nervous system. This compound is essential for researchers and manufacturers in the pharmaceutical and biotechnology sectors, particularly those focused on neuropharmacology and the development of new chemical entities.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the multi-step synthesis of potential drug candidates, particularly for neurological and psychiatric disorders.
• Reference Standard: Used in analytical laboratories for method development, validation, and quality control (QC/QA) of active pharmaceutical ingredients (APIs) and related substances.
• Biochemical Research: Serves as a tool compound in pharmacological studies to investigate receptor binding affinity, enzyme inhibition, and other structure-activity relationship (SAR) studies.
• Process Chemistry Development: Employed in route scouting and optimization for the scalable production of complex molecules within R&D and pilot plant settings.
• Academic Research: Utilized in university and institutional labs for synthetic organic chemistry projects and the exploration of new heterocyclic reaction methodologies.

Basic Information

Item	Detail
Product Name	Pd 125,530, trans-(±)-3,4,4A,10B-Tetrahydro-4-Propyl-2H,5H-[1]Benzopyrano[4,3-B]-1,4-Oxazin-9-Ol Hydrochloride
CAS No.	112960-16-4
Molecular Formula	C17H23NO3·HCl
Molecular Weight	325.83 g/mol (Free base: 289.37 g/mol)
Synonyms	Pd-125530; Pd125530; trans-(±)-3,4,4a,10b-Tetrahydro-4-propyl-2H,5H-[1]benzopyrano[4,3-b]-1,4-oxazin-9-ol hydrochloride; 9-Hydroxy-4-propyl-2,3,4a,10b-tetrahydro-5H-[1]benzopyrano[4,3-b][1,4]oxazine hydrochloride; (±)-trans-9-Hydroxy-4-propyl-2,3,4a,10b-tetrahydro-5H-1-benzopyrano[4,3-b][1,4]oxazine hydrochloride
EINECS	Contact for details

Quality Control

Our Pd 125,530 hydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and chiral assay, NMR and MS for structural confirmation, and tests for residual solvents and moisture content (KF). We provide a detailed Certificate of Analysis (COA) with every shipment, ensuring traceability and compliance with your research or cGMP guidelines for advanced intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container should be kept in a desiccated environment. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Retention time corresponds to reference standard
Identification (IR)	Spectrum matches reference
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% trans-(±) isomer
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Heavy Metals	< 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.