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2'- And 3'-o-(4-Benzoylbenzoyl)-Adenosine 5'-Triphosphate Triethylammonium Salt CAS NO 112898-15-4
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CAS No.:112898-15-4
Grade:Pharmacy Grade
Content:99.9%
Brand:Customizable
Packaging:Customizable
Description
2'- And 3'-o-(4-Benzoylbenzoyl)-Adenosine 5'-Triphosphate Triethylammonium Salt is a chemically modified, photoactivatable analog of adenosine triphosphate (ATP) designed for advanced biochemical research. This compound is a critical tool for studying ATP-dependent enzymes and processes, allowing for precise, light-induced cross-linking to identify binding sites and protein interactions. It is primarily utilized by researchers and scientists in biochemistry, enzymology, and structural biology for mechanistic studies and probe development.
Application
- Enzyme Mechanism Studies: As a photoaffinity labeling agent to covalently trap ATP-binding sites in enzymes and receptors upon UV irradiation.
- Protein-Protein Interaction Mapping: To identify and characterize proteins that interact with ATP or nucleotide-binding domains.
- Structural Biology Probes: Used in the development of probes for X-ray crystallography, cryo-EM, or NMR to elucidate enzyme active site architecture.
- Kinase and ATPase Research: A vital reagent for investigating the function and regulation of kinases, ATPases, and other ATP-utilizing proteins.
- Signal Transduction Pathways: Employed to study energy-dependent signaling cascades and metabolic pathways within cells.
- Drug Discovery Screening: Used in assays to identify and characterize novel inhibitors or modulators of ATP-binding targets.
Basic Information
| Product Name | 2'- And 3'-o-(4-Benzoylbenzoyl)-Adenosine 5'-Triphosphate Triethylammonium Salt |
| CAS No. | 112898-15-4 |
| Molecular Formula | C39H49N8O17P3 • C6H15N |
| Molecular Weight | ~1057.9 g/mol (free acid), as triethylammonium salt |
| Synonyms | BzATP Triethylammonium Salt; Bz-ATP; 2'(3')-O-(4-Benzoylbenzoyl)adenosine-5'-triphosphate triethylammonium salt; 2',3'-O-(4-Benzoylbenzoyl)adenosine-5'-triphosphate triethylammonium salt; Bz-ATP, triethylammonium salt; BzATP, Et3NH+ salt; Photoactivatable ATP analog; caged ATP analog (benzophenone); Bz2ATP |
| EINECS | Contact for details |
Quality Control
Our 2'- And 3'-o-(4-Benzoylbenzoyl)-Adenosine 5'-Triphosphate Triethylammonium Salt is produced and handled under strict quality protocols suitable for research applications. Each batch undergoes rigorous analytical testing to ensure high purity, identity, and functional integrity. Certificates of Analysis (COA) detailing purity, HPLC profile, and other relevant specifications are available upon request to support your research documentation needs.
Storage
Preserve in a tightly closed container, protected from light. Store at -20°C or below in a desiccated environment. This product is hygroscopic (moisture-sensitive). For long-term stability, store under inert atmosphere. Allow the vial to equilibrate to room temperature before opening to minimize moisture uptake.
Specification
| Item | Specification |
|---|---|
| Appearance | White to off-white powder or solid |
| Identification (HPLC) | Conforms to reference standard |
| Identification (NMR) | Conforms to structure |
| Purity (HPLC) | ≥ 95% |
| Water Content (KF) | ≤ 3.0% |
| Solubility | Soluble in DMSO, Methanol, Water |
| Functional Activity | Tested in standard photo-crosslinking assay |
Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.
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