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2'- And 3'-o-(4-Benzoylbenzoyl)-Adenosine 5'-Triphosphate Triethylammonium Salt CAS NO 112898-15-4


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CAS No.:112898-15-4

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

2'- And 3'-o-(4-Benzoylbenzoyl)-Adenosine 5'-Triphosphate Triethylammonium Salt is a chemically modified, photoactivatable analog of adenosine triphosphate (ATP) designed for advanced biochemical research. This compound is a critical tool for studying ATP-dependent enzymes and processes, allowing for precise, light-induced cross-linking to identify binding sites and protein interactions. It is primarily utilized by researchers and scientists in biochemistry, enzymology, and structural biology for mechanistic studies and probe development.

Application

  • Enzyme Mechanism Studies: As a photoaffinity labeling agent to covalently trap ATP-binding sites in enzymes and receptors upon UV irradiation.
  • Protein-Protein Interaction Mapping: To identify and characterize proteins that interact with ATP or nucleotide-binding domains.
  • Structural Biology Probes: Used in the development of probes for X-ray crystallography, cryo-EM, or NMR to elucidate enzyme active site architecture.
  • Kinase and ATPase Research: A vital reagent for investigating the function and regulation of kinases, ATPases, and other ATP-utilizing proteins.
  • Signal Transduction Pathways: Employed to study energy-dependent signaling cascades and metabolic pathways within cells.
  • Drug Discovery Screening: Used in assays to identify and characterize novel inhibitors or modulators of ATP-binding targets.

Basic Information

Product Name 2'- And 3'-o-(4-Benzoylbenzoyl)-Adenosine 5'-Triphosphate Triethylammonium Salt
CAS No. 112898-15-4
Molecular Formula C39H49N8O17P3 • C6H15N
Molecular Weight ~1057.9 g/mol (free acid), as triethylammonium salt
Synonyms BzATP Triethylammonium Salt; Bz-ATP; 2'(3')-O-(4-Benzoylbenzoyl)adenosine-5'-triphosphate triethylammonium salt; 2',3'-O-(4-Benzoylbenzoyl)adenosine-5'-triphosphate triethylammonium salt; Bz-ATP, triethylammonium salt; BzATP, Et3NH+ salt; Photoactivatable ATP analog; caged ATP analog (benzophenone); Bz2ATP
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Quality Control

Our 2'- And 3'-o-(4-Benzoylbenzoyl)-Adenosine 5'-Triphosphate Triethylammonium Salt is produced and handled under strict quality protocols suitable for research applications. Each batch undergoes rigorous analytical testing to ensure high purity, identity, and functional integrity. Certificates of Analysis (COA) detailing purity, HPLC profile, and other relevant specifications are available upon request to support your research documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a desiccated environment. This product is hygroscopic (moisture-sensitive). For long-term stability, store under inert atmosphere. Allow the vial to equilibrate to room temperature before opening to minimize moisture uptake.

Specification

Item Specification
Appearance White to off-white powder or solid
Identification (HPLC) Conforms to reference standard
Identification (NMR) Conforms to structure
Purity (HPLC) ≥ 95%
Water Content (KF) ≤ 3.0%
Solubility Soluble in DMSO, Methanol, Water
Functional Activity Tested in standard photo-crosslinking assay

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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