Description

1-Bromo-2,4,5-Trifluoro-3-Methylbenzene is a high-purity halogenated aromatic building block of significant importance in advanced organic synthesis. Its unique trifluoro-methyl-bromo substitution pattern makes it a critical intermediate for constructing complex molecules with tailored electronic and steric properties. This compound is primarily utilized by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for the development of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon for the synthesis of fluorinated drug candidates, particularly in oncology and central nervous system (CNS) therapeutic areas.
• Agrochemical Active Ingredient Synthesis: Used in the production of advanced herbicides and pesticides, where the fluorine atoms enhance biological activity and environmental stability.
• Liquid Crystal & OLED Material Precursor: Serves as a building block for fluorinated aromatic cores in electronic materials for displays and lighting.
• Cross-Coupling Reactions: An excellent substrate for Suzuki, Stille, and other palladium-catalyzed cross-coupling reactions to create biaryl structures.
• Functionalized Ligand Synthesis: Employed in the preparation of specialized ligands for catalysis and material science applications.
• Research & Development: A versatile reagent for academic and industrial R&D exploring new fluorinated chemical entities.

Basic Information

Item	Details
Product Name	1-Bromo-2,4,5-Trifluoro-3-Methylbenzene
CAS No.	112822-82-9
Molecular Formula	C7H3BrF3
Molecular Weight	223.00 g/mol
Synonyms	2,4,5-Trifluoro-3-methylbromobenzene; 3-Methyl-2,4,5-trifluorobromobenzene; 1-Bromo-2,4,5-trifluoro-3-methyl-benzene; Benzene, 1-bromo-2,4,5-trifluoro-3-methyl-; 2-Bromo-1,3,4-trifluoro-6-methylbenzene (alternative numbering)
EINECS	Contact for details

Quality Control

Our 1-Bromo-2,4,5-Trifluoro-3-Methylbenzene is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including GC, HPLC, and NMR, to ensure high chemical purity and identity confirmation. A comprehensive Certificate of Analysis (COA) detailing purity, impurity profile, and physical properties is provided with every shipment to guarantee batch-to-batch consistency and support your regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flames. Due to its light-sensitive nature, containers should be kept in opaque packaging or amber glass.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC)	≥ 98.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.