Description

Ins(345)P3*3Na is the trisodium salt of D-myo-inositol 1,3,4-trisphosphate, a high-purity, biologically active isomer of inositol trisphosphate. This compound serves as a critical research-grade biochemical tool for studying intracellular calcium signaling pathways and phosphoinositide metabolism. It is primarily utilized by pharmaceutical researchers, academic institutions, and diagnostic developers working in cell biology, neuroscience, and drug discovery.

Application

• Cell Signaling Research: As a specific agonist for IP3 receptor subtypes to study calcium release from endoplasmic reticulum stores.
• Neuroscience Studies: Investigation of synaptic transmission, neuronal excitability, and roles in neurological disorders.
• Drug Discovery & Screening: Used in high-throughput assays to identify and characterize modulators of the IP3 receptor for therapeutic development.
• Biochemical Reagent: A key standard and substrate in enzymatic studies of phosphatases and kinases within the inositol phosphate pathway.
• Diagnostic Development: Potential use in developing assays for monitoring phosphoinositide-related metabolic diseases.

Basic Information

Product Name	Ins(345)P3*3Na
CAS No.	112791-62-5
Molecular Formula	C6H12Na3O18P3
Molecular Weight	552.06 g/mol
Synonyms	D-myo-Inositol 1,3,4-Trisphosphate Trisodium Salt; Ins(1,3,4)P3 Trisodium Salt; Inositol 1,3,4-Trisphosphate Trisodium Salt; IP3 (1,3,4) Trisodium Salt; 1D-myo-Inositol 1,3,4-trisphosphate trisodium salt; D-myo-Inositol-1,3,4-trisphosphate, trisodium salt; Ins(1,3,4)P3
EINECS	Contact for details

Quality Control

Our Ins(345)P3*3Na is manufactured under strict quality systems to ensure batch-to-batch consistency and high biological activity. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and performance data. We adhere to rigorous analytical standards suitable for critical life science research, with specifications available for review.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This material is hygroscopic (moisture-sensitive); allow the sealed vial to equilibrate to room temperature before opening to minimize moisture uptake.

Specification

Item	Specification
Appearance	White to off-white powder or solid
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 5.0%
Biological Activity (Calcium Release Assay)	Conforms to expected activity range

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.