Description

1-Bromo-2-Pentafluoroethyl-Benzene is a high-value fluorinated aromatic building block characterized by its unique combination of a bromine substituent and a pentafluoroethyl group. This compound is essential for introducing both fluorine content and a reactive halogen site into advanced molecular architectures. It is primarily utilized by researchers and process chemists in the pharmaceutical, agrochemical, and specialty materials sectors for applications requiring precise fluorination and subsequent functionalization.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for introducing fluorinated aromatic motifs that can enhance metabolic stability and bioavailability.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides where the pentafluoroethyl group can improve lipophilicity and environmental persistence.
• Liquid Crystal & OLED Materials: Acts as a building block for fluorinated components in electronic display materials and organic light-emitting diodes (OLEDs), where fluorine atoms help tune electronic properties and stability.
• Polymer & Resin Modification: Employed to incorporate fluorine into polymers, enhancing properties such as chemical resistance, thermal stability, and surface characteristics.
• Cross-Coupling Reactions: The bromine atom makes it an excellent substrate for palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Heck, Sonogashira) to create complex biaryl and other structures.
• Fluorinated Surfactant & Coating Precursor: Used in the synthesis of specialty surfactants and surface treatment agents that require low surface energy and high stability.

Basic Information

Product Name	1-Bromo-2-Pentafluoroethyl-Benzene
CAS No.	112754-17-3
Molecular Formula	C8H4BrF5
Molecular Weight	275.02 g/mol
Synonyms	2-Bromo-α,α,α,β,β-pentafluoroethylbenzene; 1-Bromo-2-(pentafluoroethyl)benzene; 2-(Pentafluoroethyl)bromobenzene; o-Bromopentafluoroethylbenzene; Benzene, 1-bromo-2-(pentafluoroethyl)-; 2-Bromo-1-(pentafluoroethyl)benzene; (2-Bromophenyl)pentafluoroethane
EINECS	Contact for details

Quality Control

Our 1-Bromo-2-Pentafluoroethyl-Benzene is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including GC, HPLC, and NMR, to ensure high purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area away from incompatible materials such as strong acids and bases. Recommended storage temperature is between 2°C and 25°C. Keep container tightly sealed when not in use to prevent moisture absorption and degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC)	≥ 98.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.