Description

2-Chloro-6-Methylbenzotrifluoride is a versatile fluorinated aromatic building block of significant importance in advanced organic synthesis. Its value lies in the combination of a reactive chlorine substituent and a stable, electron-withdrawing trifluoromethyl group, enabling precise molecular modifications. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, where it serves as a key intermediate for creating active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for molecules requiring a trifluoromethylphenyl moiety to modulate bioavailability and metabolic stability.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and insecticides, where the trifluoromethyl group enhances biological activity and environmental persistence.
• Liquid Crystal & OLED Materials: Serves as a building block for fluorinated components in electronic display technologies, contributing to improved dielectric anisotropy and thermal stability.
• Functional Polymer Monomer: Incorporated into specialty polymers to impart unique chemical resistance, low surface energy, and optical properties.
• Organic Synthesis Reagent: Employed in cross-coupling reactions (e.g., Suzuki, Negishi) and nucleophilic aromatic substitution to introduce complex aromatic systems.
• Dye & Pigment Intermediate: Used in the development of high-performance, light-fast colorants and imaging agents.

Basic Information

Product Name	2-Chloro-6-Methylbenzotrifluoride
CAS No.	112641-25-5
Molecular Formula	C8H6ClF3
Molecular Weight	194.58 g/mol
Synonyms	1-Chloro-2-methyl-3-(trifluoromethyl)benzene; 2-Chloro-α,α,α-trifluoro-o-xylene; 2-Chloro-6-(trifluoromethyl)toluene; 3-Trifluoromethyl-2-chlorotoluene; 2-Methyl-6-chlorobenzotrifluoride; o-Chloro-α,α,α-trifluoro-m-xylene; Benzene, 1-chloro-2-methyl-3-(trifluoromethyl)-
EINECS	Contact for details

Quality Control

Our 2-Chloro-6-Methylbenzotrifluoride is manufactured under a strict quality management system. Every batch undergoes comprehensive analytical testing, including GC, HPLC, and NMR, to ensure high chemical purity and identity confirmation. We provide a detailed Certificate of Analysis (COA) with each shipment, documenting all critical parameters. Our quality commitment aligns with cGMP principles where required, ensuring reliability for your most sensitive synthesis workflows.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area away from incompatible materials such as strong acids and bases. Recommended storage temperature is between 15°C and 25°C. Keep container tightly sealed when not in use to prevent moisture absorption and maintain product integrity.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (GC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Related Substances (GC)	Total impurities ≤ 2.0%
Density (at 20°C)	~1.35 g/cm³

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.