Description

6-Epitetrodotoxin is a potent neurotoxin analog, structurally related to tetrodotoxin (TTX), which acts as a highly selective sodium channel blocker. This compound is of significant value in neuroscience and pharmacological research for studying voltage-gated sodium channels and neuronal signaling pathways. It is primarily utilized by research institutions, pharmaceutical R&D departments, and diagnostic manufacturers for developing novel therapeutics and investigative tools.

Application

• Neuroscience Research: As a selective sodium channel blocker for electrophysiological studies and neuronal activity modulation.
• Pharmacological Tool Compound: Used in high-throughput screening (HTS) and target validation for drug discovery programs focused on pain, anesthesia, and neurological disorders.
• Biochemical Assay Development: Serves as a key reagent in developing assays to study ion channel function and inhibitor potency.
• Toxin Standard: Acts as a reference standard in analytical chemistry and toxicology for the detection and quantification of tetrodotoxin analogs.
• Academic Research: Fundamental studies on the structure-activity relationship (SAR) of sodium channel blockers and marine toxins.

Basic Information

Product Name	6-Epitetrodotoxin
CAS No.	112318-40-8
Molecular Formula	C11H17N3O8
Molecular Weight	319.27 g/mol
Synonyms	6-epi-TTX; 6-epi-Tetrodotoxin; 4,9-Anhydro-6-epitetrodotoxin; Tetrodotoxin, 6-epi-; 6-Epi-TTX; 6-Epitetrodotoxin (TTX analog); 6-epi-Tetrodotoxin (6-epi-TTX)
EINECS	Contact for details

Quality Control

Our 6-Epitetrodotoxin is produced under stringent quality management systems to ensure batch-to-batch consistency and high purity for research applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to relevant standards for research-grade biochemicals, ensuring reliable performance in sensitive applications.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below. The product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (MS)	Conforms
Purity (HPLC)	≥95%
Water Content (KF)	≤5.0%
Residue on Ignition	≤1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.