Description

2,4,5-Trifluorobenzotrifluoride is a high-value fluorinated aromatic building block essential for advanced organic synthesis. Its unique structure, featuring both trifluoromethyl and multiple fluorine substituents, makes it a critical intermediate for introducing lipophilicity and metabolic stability into target molecules. This compound is primarily sought by research and development teams in the pharmaceutical and agrochemical industries for creating novel active ingredients, as well as by manufacturers of specialty materials like liquid crystals and electronic chemicals.

Application

• Pharmaceutical Intermediate: Key synthon for the development of active pharmaceutical ingredients (APIs), particularly in kinase inhibitors and CNS-targeting drugs.
• Agrochemical Synthesis: Building block for novel herbicides, fungicides, and pesticides, leveraging the trifluoromethyl group's bioactivity.
• Liquid Crystal Materials: Used in the synthesis of fluorinated liquid crystals for high-performance displays (LCDs).
• Electronic Chemicals: Intermediate in the production of specialty chemicals for semiconductors and dielectric fluids.
• Organic Synthesis Reagent: Serves as a versatile precursor for cross-coupling reactions (e.g., Suzuki, Negishi) to create complex fluorinated aromatics.
• Material Science Research: Employed in R&D for novel polymers and coatings with enhanced chemical resistance and weatherability.

Basic Information

Product Name	2,4,5-Trifluorobenzotrifluoride
CAS No.	112290-07-0
Molecular Formula	C7H2F6
Molecular Weight	200.08 g/mol
Synonyms	1,2,4-Trifluoro-5-(trifluoromethyl)benzene; 2,4,5-Trifluoro-α,α,α-trifluorotoluene; 2,4,5-Trifluorobenzylidene trifluoride; 2,4,5-Trifluoro(trifluoromethyl)benzene; α,α,α,2,4,5-Hexafluorotoluene; Benzene, 1,2,4-trifluoro-5-(trifluoromethyl)-; TFB-TF
EINECS	Contact for details

Quality Control

Our 2,4,5-Trifluorobenzotrifluoride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including GC, HPLC, and NMR, to ensure high purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area away from incompatible materials such as strong acids and organic solvents. Recommended storage temperature is 2-8°C for long-term stability. Keep container tightly sealed when not in use to prevent moisture absorption and volatilization.

Specification

Item	Specification
Appearance	Colorless to pale yellow clear liquid
Identification (IR)	Conforms to structure
Purity (GC)	≥ 98.0%
Water Content (KF)	≤ 0.1%
Related Substances (GC)	Individual impurity ≤ 0.5%, Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.