Description

2-Bromo-4,5-Difluorobenzotrifluoride is a versatile fluorinated aromatic building block of significant importance in advanced organic synthesis. Its molecular structure, featuring bromine and fluorine substituents on a trifluoromethylated benzene ring, makes it a critical intermediate for constructing complex molecules with tailored electronic and steric properties. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty materials sectors who require high-purity intermediates for developing new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon in the synthesis of active pharmaceutical ingredients (APIs), particularly for molecules requiring fluorinated aromatic cores to modulate bioavailability, metabolic stability, and binding affinity.
• Agrochemical Synthesis: Used in the development of next-generation herbicides, fungicides, and insecticides, where the introduction of fluorine and bromine atoms enhances biological activity and environmental persistence.
• Liquid Crystal & OLED Materials: Serves as a precursor for fluorinated compounds used in electronic display technologies, contributing to improved dielectric anisotropy and thermal stability.
• Polymer & Resin Modification: Incorporated as a monomer or cross-linking agent to create specialty polymers with enhanced chemical resistance, lower dielectric constants, and unique surface properties.
• Organic Synthesis Building Block: Utilized in cross-coupling reactions (e.g., Suzuki, Stille) and nucleophilic aromatic substitutions to introduce functionalized difluorobenzotrifluoride motifs into complex molecular architectures.
• Research & Development: Employed in academic and industrial R&D labs for exploring new synthetic methodologies and creating novel fluorinated compounds for various high-tech applications.

Basic Information

Product Name	2-Bromo-4,5-Difluorobenzotrifluoride
CAS No.	112290-04-7
Molecular Formula	C7H2BrF5
Molecular Weight	260.99 g/mol
Synonyms	1-Bromo-2,3-difluoro-4-(trifluoromethyl)benzene; 2,3-Difluoro-4-(trifluoromethyl)bromobenzene; 2-Bromo-1,2-difluoro-3-(trifluoromethyl)benzene; Benzene, 1-bromo-2,3-difluoro-4-(trifluoromethyl)-; 4-(Trifluoromethyl)-2,3-difluorobromobenzene; 2-Bromo-4,5-difluoro-α,α,α-trifluorotoluene
EINECS	Contact for details

Quality Control

Our 2-Bromo-4,5-Difluorobenzotrifluoride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including GC, HPLC, and NMR, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all relevant specifications. Our quality commitment ensures the material meets the stringent requirements for use in regulated synthesis and advanced research applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from strong bases and incompatible organic solvents. For long-term storage, consider storing under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Density (at 20°C)	~1.8 g/cm³

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.