Description

5-Trifluoromethyl-Pyridin-3-Ylamine is a high-purity fluorinated pyridine derivative, serving as a critical building block in advanced organic synthesis. Its value lies in the unique reactivity and electronic properties imparted by the trifluoromethyl and amine functional groups on the pyridine ring. This compound is essential for research and development chemists in the pharmaceutical and agrochemical industries, where it is used to create novel active ingredients with enhanced metabolic stability and bioavailability.

Application

• Pharmaceutical Intermediate: A key synthon for the development of active pharmaceutical ingredients (APIs), particularly in kinase inhibitors and central nervous system (CNS) targeted drugs.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides, leveraging the trifluoromethyl group to improve efficacy and environmental profile.
• Material Science Precursor: Employed in the synthesis of functionalized ligands for catalysis and in the creation of novel fluorinated polymers or liquid crystals.
• Chemical Research & Development: Serves as a versatile scaffold in medicinal chemistry for structure-activity relationship (SAR) studies and library synthesis.
• Fluorine Chemistry Building Block: Utilized in the synthesis of more complex fluorinated heterocycles and fine chemicals.

Basic Information

Product Name	5-Trifluoromethyl-Pyridin-3-Ylamine
CAS No.	112110-07-3
Molecular Formula	C7H5F3N2
Molecular Weight	162.12 g/mol
Synonyms	3-Amino-5-(trifluoromethyl)pyridine; 5-(Trifluoromethyl)pyridin-3-amine; 3-Amino-5-trifluoromethylpyridine; 5-Trifluoromethyl-3-pyridinamine; 5-Trifluoromethyl-3-aminopyridine; 3-Pyridinamine, 5-(trifluoromethyl)-; 5-Trifluoromethyl-3-pyridylamine
EINECS	Contact for details

Quality Control

Our 5-Trifluoromethyl-Pyridin-3-Ylamine is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high chemical purity and identity confirmation. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all relevant specifications. Our quality commitment ensures material consistency and reliability for your critical R&D and production processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); keep the container tightly sealed in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.