Description

Argiotoxin 673 is a potent and highly selective glutamate receptor antagonist, specifically targeting ionotropic receptors. This compound is a critical research tool for neuropharmacological studies, enabling precise investigation of synaptic transmission and excitatory signaling pathways. It is primarily utilized by neuroscience researchers, pharmaceutical R&D teams, and academic institutions focused on neurological disorders and receptor characterization.

Application

• Neuroscience Research: As a selective antagonist for studying the function and pharmacology of glutamate-gated ion channels (AMPA/kainate receptors).
• Neuropharmacology: Used in electrophysiological experiments to block specific synaptic currents and elucidate excitatory neurotransmission mechanisms.
• Drug Discovery: Serves as a reference compound and pharmacological tool in high-throughput screening assays for neurological drug candidates.
• Toxicology Studies: Employed in research on neurotoxic agents and the development of potential neuroprotective strategies.
• Biochemical Assays: Used in receptor binding studies and the characterization of ligand-receptor interactions in vitro.
• Academic & Institutional R&D: Fundamental research tool for universities and institutes exploring synaptic plasticity, neurodegeneration, and CNS disorders.

Basic Information

Product Name	Argiotoxin 673
CAS No.	111924-44-8
Molecular Formula	C41H67N13O11S2
Molecular Weight	958.2 g/mol
Synonyms	ArgTX-673; Argiotoxin-673; AR-673; Philanthotoxin-343 analogue; Glutamate receptor antagonist AR-673; Polyamine amide neurotoxin; JSTX-3 analogue; AMPA/kainate receptor blocker
EINECS	Contact for details

Quality Control

Our Argiotoxin 673 is produced and handled under strict quality management protocols to ensure batch-to-batch consistency and reliability for research applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and stability data. We adhere to relevant standards for research-grade biochemicals to support reproducible scientific results.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. Due to its hygroscopic (moisture-sensitive) nature, containers should be allowed to equilibrate to room temperature before opening to minimize moisture ingress. For long-term storage, consider under inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC/MS)	Conforms
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 2.0%
Solubility	Soluble in DMSO, Methanol

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.