Description

o-Cresol -D-Glucuronide is a high-purity reference standard and biochemical reagent, specifically the D-glucuronide conjugate of o-cresol. This compound is of critical importance for analytical research and method development, serving as a definitive marker for metabolic and exposure studies. It is primarily needed by pharmaceutical R&D laboratories, contract research organizations (CROs), and diagnostic manufacturers focused on toxicology, drug metabolism, and biomarker analysis.

Application

• Biomarker Reference Standard: Used as a certified reference material for the quantitative analysis of o-cresol metabolites in biological samples (e.g., urine, plasma).
• Toxicology & Exposure Studies: Essential for calibrating equipment and validating methods in occupational and environmental health monitoring.
• Drug Metabolism & Pharmacokinetics (DMPK): Employed in research to study Phase II conjugation pathways and glucuronidation kinetics.
• Diagnostic Assay Development: Serves as a key component in the development and calibration of clinical diagnostic kits and immunoassays.
• Academic & Government Research: Utilized in universities and regulatory bodies for fundamental research on xenobiotic metabolism and biochemical pathways.
• Quality Control (QC) in Manufacturing: Acts as an internal standard for QC laboratories in pharmaceutical and chemical industries to ensure product and process consistency.

Basic Information

Product Name	o-Cresol -D-Glucuronide
CAS No.	111897-99-5
Molecular Formula	C₁₃H₁₆O₈
Molecular Weight	300.26 g/mol
Synonyms	2-Methylphenyl β-D-Glucopyranosiduronic Acid; o-Cresol Glucuronide; 2-Cresol D-Glucuronide; (2-Methylphenoxy)-β-D-glucopyranosiduronic Acid; o-Cresol β-D-Glucuronide; 2-Methylphenyl-β-D-glucuronide; o-Methylphenyl-β-D-glucuronide; β-D-Glucopyranosiduronic acid, 2-methylphenyl-
EINECS	Contact for details

Quality Control

Our o-Cresol -D-Glucuronide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the high standards required for research and reference applications. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) or as indicated on the label/COA. Keep the container in a dry, cool, and well-ventilated area. For long-term storage, consider storing desiccated at -20°C.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms to reference spectrum
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.