Description

3,5-Dimethylbenzylmagnesium Bromide is a highly reactive Grignard reagent, a cornerstone in modern synthetic organic chemistry for the formation of carbon-carbon bonds. Its value lies in enabling the efficient and selective introduction of the 3,5-dimethylbenzyl group into complex molecular frameworks, a key step in pharmaceutical and advanced material synthesis. This compound is essential for R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries seeking to build novel aromatic structures.

Application

• Pharmaceutical Intermediate Synthesis: A critical building block for constructing active pharmaceutical ingredients (APIs), particularly those requiring substituted benzyl motifs.
• Agrochemical Development: Used in the synthesis of novel herbicides, fungicides, and insecticides where the dimethylbenzyl group imparts specific biological activity.
• Ligand and Catalyst Preparation: Serves as a precursor for synthesizing specialized phosphine or N-heterocyclic carbene (NHC) ligands used in asymmetric catalysis.
• Material Science Research: Employed in the creation of advanced organic materials, such as liquid crystals or organic semiconductors, with tailored electronic properties.
• Fine Chemical Manufacturing: Facilitates the production of specialty aromatics, flavors, and fragrances through precise benzylation reactions.

Basic Information

Product Name	3,5-Dimethylbenzylmagnesium Bromide
CAS No.	111823-36-0
Molecular Formula	C9H11BrMg
Molecular Weight	223.39 g/mol
Synonyms	Magnesium, bromo(3,5-dimethylphenyl)methyl-; (3,5-Dimethylbenzyl)magnesium bromide; 1-(Bromomagnesio)methyl-3,5-dimethylbenzene; 3,5-Dimethylbenzylmagnesium bromide solution; 3,5-Xylylmagnesium bromide; Grignard reagent, 3,5-dimethylbenzylmagnesium bromide
EINECS	Contact for details

Quality Control

Every batch of our 3,5-Dimethylbenzylmagnesium Bromide is manufactured and tested under stringent quality management systems. We provide comprehensive analytical data to ensure batch-to-batch consistency and reliability for your critical synthesis steps. A detailed Certificate of Analysis (COA), including titration assay for Grignard concentration and GC analysis for solvent purity and byproducts, is supplied with each shipment.

Storage

Preserve in a tightly closed container, protected from light. This product is highly volatile, easily oxidized, and must be stored under a dry, inert atmosphere (argon or nitrogen) at recommended temperatures of 2°C to 8°C. Keep away from moisture, heat, and incompatible materials such as strong acids, oxidizers, and protic solvents. Use appropriate explosion-proof refrigeration.

Specification

Item	Specification
Appearance	Clear, colorless to light yellow solution
Concentration (in THF or Ether)	0.5 M - 2.0 M (Custom concentrations available)
Assay (by Titration)	≥ 95% (as Grignard reagent)
Solvent	Specified (Tetrahydrofuran, Diethyl ether, or Toluene)
Identification (IR/NMR)	Conforms to structure

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.