Description

Naltriben Mesylate CAS NO 111555-58-9 is a selective and potent delta opioid receptor (DOR) antagonist. This compound is a critical research tool for investigating the complex pharmacology of the opioid system, particularly the role of delta receptors in pain modulation, addiction, and mood disorders. It is essential for pharmaceutical R&D, academic neuroscience research, and the development of novel therapeutic agents targeting opioid pathways.

Application

• Neuroscience Research: A key pharmacological probe for studying delta opioid receptor (DOR) function and signaling in vitro and in vivo.
• Pain Mechanism Studies: Used to elucidate the specific role of DOR in pain perception, tolerance, and the development of new analgesic strategies.
• Addiction Research: Investigates the involvement of delta receptors in drug reward, reinforcement, and relapse behaviors for substances like opioids and alcohol.
• Psychiatric Disorder Models: Applied in research exploring the link between the opioid system and conditions such as depression and anxiety.
• Pharmaceutical Development: Serves as a reference standard and lead compound in the discovery of selective DOR antagonists or inverse agonists for therapeutic use.
• Biochemical Assays: Used in receptor binding studies, functional assays (e.g., GTPγS), and cellular signaling experiments to characterize compound activity.

Basic Information

Product Name	Naltriben Mesylate
CAS No.	111555-58-9
Molecular Formula	C₂₈H₃₂N₂O₅S
Molecular Weight	508.63 g/mol
Synonyms	17-Cyclopropylmethyl-6,7-dehydro-4,5α-epoxy-3,14-dihydroxy-6,7,2',3'-indolomorphinan Mesylate; NTB Mesylate; Naltriben Methanesulfonate; (5α)-17-(Cyclopropylmethyl)-6,7-didehydro-4,5-epoxy-3,14-dihydroxy-6,7,2',3'-indolomorphinan Methanesulfonate
EINECS	Contact for details

Quality Control

Our Naltriben Mesylate is manufactured under strict quality control protocols to ensure high purity and batch-to-batch consistency, suitable for sensitive research applications. Each lot is characterized using advanced analytical techniques including HPLC, NMR, and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); ensure the container is sealed tightly after each use to minimize exposure to atmospheric humidity. For long-term storage, consider desiccants.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥98.0%
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm
Single Unknown Impurity (HPLC)	≤0.5%
Total Impurities (HPLC)	≤2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.