Description

Descladinose 6-n-Desmethyl Azithromycin is a key intermediate in the synthesis of advanced macrolide antibiotics and novel pharmaceutical compounds. This high-purity intermediate is critical for research and development efforts aimed at creating new therapeutic agents with improved efficacy and safety profiles. It is primarily utilized by pharmaceutical R&D laboratories, fine chemical manufacturers, and academic institutions engaged in antibiotic development and medicinal chemistry.

Application

• Pharmaceutical Intermediate: A crucial building block in the synthesis of next-generation macrolide antibiotics and their derivatives.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies to develop novel antibacterial agents with modified pharmacokinetic properties.
• Reference Standard: Serves as a high-purity analytical standard for quality control and impurity profiling in azithromycin-related API manufacturing.
• Process Development: Employed in the optimization and scaling of synthetic routes for complex antibiotic molecules in pilot plants.
• Academic & Institutional Research: Facilitates fundamental research into antibiotic mechanisms, resistance, and the development of new chemical entities.

Basic Information

Product Name	Descladinose 6-n-Desmethyl Azithromycin
CAS No.	111247-94-0
Molecular Formula	C37H71N2O12
Molecular Weight	735.98 g/mol
Synonyms	6-Desmethylazithromycin; 6-De-O-methylazithromycin; 6-Nor-6-demethylazithromycin; Azithromycin Impurity G; Azithromycin 6-N-Desmethyl; 9-Deoxo-9a-aza-9a-methyl-9a-homoerythromycin A 6-Desmethyl Derivative; (2R,3S,4R,5R,8R,10R,11R,12S,13S,14R)-11-[(2S,3R,4S,6R)-4-(Dimethylamino)-3-hydroxy-6-methyloxan-2-yl]oxy-2-ethyl-3,4,10-trihydroxy-13-[(2R,4R,5S,6S)-5-hydroxy-4-methoxy-4,6-dimethyloxan-2-yl]oxy-3,5,6,8,10,12,14-heptamethyl-1-oxa-6-azacyclopentadecan-15-one
EINECS	Contact for details

Quality Control

Our Descladinose 6-n-Desmethyl Azithromycin is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via IR and NMR spectroscopy, to ensure it meets the high standards required for pharmaceutical R&D. Certificates of Analysis (COA) detailing all test results are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 1.0%
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.