Description

19,20-Dehydroprostaglandin E2 is a synthetic prostaglandin analog, a key intermediate in the research and development of bioactive lipid mediators. This compound is valued for its role in studying eicosanoid signaling pathways and their physiological effects. It is primarily utilized by pharmaceutical researchers and fine chemical manufacturers focused on inflammation, reproductive health, and metabolic disorder research.

Application

• Pharmaceutical Intermediate: A critical building block for the synthesis of novel prostaglandin-based therapeutics.
• Biochemical Research: Used as a reference standard and probe compound to investigate prostaglandin receptor (EP) activity and signaling cascades.
• Inflammation Studies: Employed in in vitro and in vivo models to elucidate the role of specific prostaglandin metabolites in inflammatory processes.
• Metabolic Pathway Analysis: A tool for studying arachidonic acid metabolism and the biosynthesis of downstream eicosanoids.
• Academic & Contract Research: Serves as a high-purity reagent for universities and CROs conducting advanced life science research.

Basic Information

Product Name	19,20-Dehydroprostaglandin E2
CAS No.	111219-93-3
Molecular Formula	C₂₀H₃₂O₅
Molecular Weight	352.47 g/mol
Synonyms	19,20-Didehydro-PGE2; (5Z,13E)-(9S,11R,15S)-9,11,15-Trihydroxy-19,20-didehydroprosta-5,13-dien-1-oic Acid; 19,20-Dehydro-PGE2; PGA2 Derivative; Prostaglandin E2 Analog; 19,20-Dehydro-PGE₂
EINECS	Contact for details

Quality Control

Our 19,20-Dehydroprostaglandin E2 is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity suitable for research applications. All materials are accompanied by a comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles. We support compliance with relevant standards for advanced pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under an inert atmosphere (e.g., argon or nitrogen) to prevent oxidation. The product is light-sensitive and easily oxidized; allow it to reach room temperature in a desiccator before opening to minimize moisture uptake.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 95.0%
Related Substances (HPLC)	Total impurities ≤ 5.0%
Solvent Residue (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.