Description

Pentafluoro(Iodomethyl)-Benzene is a high-value, multi-functional fluorinated aromatic building block. This compound is essential for introducing both pentafluorophenyl and iodomethyl functional groups in a single step, enabling precise molecular construction. It is primarily sought by R&D chemists and process developers in the pharmaceutical, agrochemical, and advanced materials sectors for synthesizing novel active ingredients and specialty polymers.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of fluorinated drug candidates, including kinase inhibitors and CNS-active compounds.
• Agrochemical Synthesis: Used to create novel fluorinated pesticides and herbicides with enhanced stability and bioavailability.
• Ligand & Catalyst Development: Serves as a versatile scaffold for constructing sophisticated pincer ligands and organocatalysts.
• Material Science: Building block for fluorinated liquid crystals, organic semiconductors, and specialty polymers with unique surface properties.
• Cross-Coupling Reactions: The iodine atom facilitates efficient Suzuki, Stille, and Sonogashira cross-coupling reactions to form complex biaryl systems.
• Radiolabeling Precursor: Potential starting material for synthesizing compounds labeled with iodine-125 for diagnostic imaging research.

Basic Information

Product Name	Pentafluoro(Iodomethyl)-Benzene
CAS No.	111196-50-0
Molecular Formula	C7H2F5I
Molecular Weight	307.99 g/mol
Synonyms	(Iodomethyl)pentafluorobenzene; Pentafluorobenzyl Iodide; α-Iodopentafluorotoluene; (Pentafluorophenyl)methyl Iodide; 1-(Iodomethyl)-2,3,4,5,6-pentafluorobenzene; Iodomethyl Pentafluorophenyl; PFB-I; C6F5CH2I
EINECS	Contact for details

Quality Control

Our Pentafluoro(Iodomethyl)-Benzene is manufactured under strict quality management systems. Each batch is characterized and tested to ensure high chemical purity and consistency, meeting the rigorous standards required for advanced synthetic applications. A comprehensive Certificate of Analysis (COA) detailing purity (typically by GC or HPLC), identity confirmation (by 1H/19F NMR, IR), and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Keep away from strong acids and incompatible organic solvents. For long-term storage, consider storing under an inert atmosphere to maximize stability.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (GC/HPLC)	≥ 97.0% (Typical 98-99%)
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.