Description

20-Dimethyl-7-Thiaprostaglandin E1 Methyl Ester is a synthetic prostaglandin analog, a key intermediate in advanced pharmaceutical research and development. This compound is valued for its structural role in the synthesis of novel therapeutic agents targeting specific biological pathways. It is primarily utilized by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in the development of new drug candidates, particularly in areas related to inflammation, vascular function, and cellular regulation.

Application

• Pharmaceutical Intermediate: A critical building block in the multi-step synthesis of novel prostaglandin-based drug candidates.
• Biochemical Research: Used as a reference standard or tool compound in pharmacological studies to investigate receptor binding and signal transduction mechanisms.
• Medicinal Chemistry: Serves as a core scaffold for structural-activity relationship (SAR) studies to optimize potency and selectivity of new chemical entities.
• Process Development: Employed in scaling up and optimizing synthetic routes for the production of advanced active pharmaceutical ingredients (APIs).
• Academic Research: Utilized in university and institutional labs for fundamental studies in organic synthesis and bioorganic chemistry.

Basic Information

Product Name	20-Dimethyl-7-Thiaprostaglandin E1 Methyl Ester
CAS No.	111037-12-8
Molecular Formula	C24H40O5S
Molecular Weight	440.64 g/mol
Synonyms	7-Thiaprostaglandin E1 Methyl Ester, 20-Dimethyl Derivative; Methyl (5Z,13E)-(9S,11R,15R)-9,11,15-Trihydroxy-20,20-dimethyl-7-thia-16,17,18,19-tetranorprosta-5,13-dien-1-oate; 20,20-Dimethyl-7-thia-PGE1 methyl ester; 7-Thia-PGE1 Methyl Ester Dimethyl Derivative; Prostaglandin E1 Thia Analog Methyl Ester; CAS 111037-12-8
EINECS	Contact for details

Quality Control

Our 20-Dimethyl-7-Thiaprostaglandin E1 Methyl Ester is produced under strict quality management systems. Each batch is subjected to comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the exacting standards required for research and development applications. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting critical quality attributes.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) or as specified on the Certificate of Analysis. Keep the container in a dry, well-ventilated place. For long-term storage, consider storing under an inert atmosphere at lower temperatures (e.g., -20°C).

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Related Substances (HPLC)	Total impurities ≤ 3.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.