Description

Cyclo-(Phenylalanyl-Tryptophyl-Lysyl-Threonyl-3-(Aminomethyl)Phenylacetic Acid) CAS NO 111010-99-2 is a synthetic cyclic peptide of significant interest in advanced pharmaceutical research and development. This compound serves as a crucial pharmacophore or structural motif for designing novel therapeutic agents, particularly in oncology and endocrinology. It is primarily utilized by pharmaceutical R&D laboratories, biotechnology companies, and academic research institutions engaged in peptide-based drug discovery.

Application

• Pharmaceutical Research: Core building block for the development of novel peptide-based drugs and targeted therapies.
• Oncology Drug Discovery: Investigation as a potential component in anticancer agents due to its specific amino acid sequence and cyclic structure.
• Hormone Analog Development: Used in the synthesis of peptide hormone analogs for metabolic and endocrine disorder research.
• Bioconjugation & Probe Synthesis: Serves as a scaffold for attaching imaging agents, fluorophores, or other functional groups in diagnostic probe development.
• Structure-Activity Relationship (SAR) Studies: Essential for mapping biological activity to specific peptide sequences in medicinal chemistry programs.
• Reference Standard: Used as a high-purity analytical standard for quality control and method validation in peptide synthesis.

Basic Information

Product Name	Cyclo-(Phenylalanyl-Tryptophyl-Lysyl-Threonyl-3-(Aminomethyl)Phenylacetic Acid)
CAS No.	111010-99-2
Molecular Formula	C43H52N8O7
Molecular Weight	792.93 g/mol
Synonyms	Cyclo(Phe-Trp-Lys-Thr-AMPA); c(Phe-Trp-Lys-Thr-AMPA); Cyclic Phe-Trp-Lys-Thr-AMPA Peptide; Cyclo(Phenylalanine-Tryptophan-Lysine-Threonine-3-(Aminomethyl)Phenylacetic Acid); 111010-99-2; Cyclic Pentapeptide c(FWKT-AMPA); AMBA-derived Cyclic Peptide; Cyclo[FWKT-3-(aminomethyl)phenylacetic acid]
EINECS	Contact for details

Quality Control

Our Cyclo-(Phenylalanyl-Tryptophyl-Lysyl-Threonyl-3-(Aminomethyl)Phenylacetic Acid) is manufactured under strict quality systems suitable for research and development applications. Each batch undergoes rigorous analytical testing, including HPLC for purity and mass spectrometry for identity confirmation, to ensure consistency and reliability. Certificates of Analysis (COA) with detailed chromatographic data are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a desiccated environment to prevent degradation. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (MS)	Conforms (M+H+ ~793.4)
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Heavy Metals	≤ 20 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.