Description

Roxatidine-D10 Hemioxalate is a deuterated analog of the histamine H2-receptor antagonist Roxatidine, specifically labeled with ten deuterium atoms. This stable isotope-labeled compound is an essential internal standard for the precise quantification of Roxatidine in complex biological matrices using advanced analytical techniques like LC-MS/MS. It is primarily required by pharmaceutical R&D laboratories, contract research organizations (CROs), and analytical testing facilities engaged in pharmacokinetic studies, drug metabolism research, and bioanalytical method development and validation.

Application

• Primary use as an internal standard for the accurate quantification of Roxatidine in bioanalytical assays.
• Critical component in LC-MS/MS method development and validation for drug metabolism and pharmacokinetics (DMPK) studies.
• Enabling precise measurement in pharmacokinetic and bioavailability studies for regulatory submissions.
• Supporting metabolite identification and profiling research in pharmaceutical development.
• Use in clinical trial sample analysis to ensure data integrity and compliance.
• Application in forensic and anti-doping analysis for definitive identification and quantification.
• Reference material for quality control in the manufacturing of active pharmaceutical ingredients (APIs).

Basic Information

Product Name	Roxatidine-D10 Hemioxalate
CAS No.	110925-88-7
Molecular Formula	C19H18D10N3O4 • 0.5C2H2O4
Molecular Weight	Contact for details
Synonyms	Roxatidine-d10; [2H10]-Roxatidine Hemioxalate; N-[3-[3-(1-Piperidinylmethyl)phenoxy]propyl]-2H10-acetohydroxamic Acid Hemioxalate; (±)-Roxatidine-d10 Hemioxalate; Roxatidine (phenyl-d5, acetyl-d5) Hemioxalate; Roxatidine-d10 (Hemioxalate Salt); Roxatidine Deuterated Internal Standard; AHR-6478-d10
EINECS	Contact for details

Quality Control

Every batch of Roxatidine-D10 Hemioxalate is manufactured and analyzed under strict quality systems to ensure the high chemical purity and isotopic enrichment required for sensitive mass spectrometry applications. Our products undergo rigorous quality testing to ensure compliance with industry standards. Certificates of Analysis (COA) are available upon request and provide detailed data on purity, isotopic purity (D-enrichment), and analytical results.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) or as indicated on the label or CoA. This product is hygroscopic (moisture-sensitive) and must be kept in a dry environment. For long-term storage, consider desiccant and inert atmosphere to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/MS)	Conforms
Purity (HPLC)	≥98.0%
Isotopic Purity (D-enrichment)	≥98.0 atom % D
Chemical Purity (NMR)	Conforms
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.