Description

Amphidinolide D CAS NO 110786-78-2 is a potent marine-derived macrolide with significant cytotoxic activity. This compound is a valuable research-grade biochemical for investigating novel anti-cancer mechanisms and cellular pathways. It is primarily utilized by pharmaceutical R&D laboratories, academic research institutions, and biotechnology companies focused on oncology drug discovery and chemical biology.

Application

• Pharmaceutical Research & Development: Serves as a key reference standard and active pharmaceutical ingredient (API) intermediate in the discovery of novel anti-cancer therapeutics.
• Biochemical Mechanism Studies: Used as a potent tool compound to study apoptosis, cell cycle arrest, and other cytotoxic mechanisms in various cancer cell lines.
• Academic Research: Employed in university and institutional labs for chemical synthesis studies, structure-activity relationship (SAR) exploration, and marine natural product research.
• High-Throughput Screening (HTS): Acts as a bioactive control or lead compound in screening libraries for identifying new molecular targets.
• Chemical Biology Probes: Utilized to develop probes for understanding specific protein interactions and signaling pathways involved in tumorigenesis.

Basic Information

Product Name	Amphidinolide D
CAS No.	110786-78-2
Molecular Formula	C32H48O8
Molecular Weight	560.73 g/mol
Synonyms	Amphidinolide D; (1S,2R,4S,5S,7S,9R,10S,11S,12S,14R,16S,18S,19S,20R,22S,23S,24S,25R,26S,27S,28S,29S,30S,31S,32S,33S,34S,35S,36S,37S,38S,39S)-2,4,5,7,9,10,11,12,14,16,18,19,20,22,23,24,25,26,27,28,29,30,31,32,33,34,35,36,37,38,39,40-Dotriacontahydroxy-1,15,17,21-tetramethyl-8,13-dioxapentacyclo[27.10.1.13,7.119,23.01,39]tetraconta-3,5,29,31,33,35,37-heptaene-6,12-dione
EINECS	Contact for details

Quality Control

Our Amphidinolide D is produced under strict quality management systems to ensure batch-to-batch consistency and high purity for research applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity confirmation, and impurity profiles. We adhere to relevant standards for research chemicals, ensuring reliable performance in sensitive biological assays.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C. Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Long-term storage at -20°C is recommended.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms to reference standard
Identification (MS)	Conforms to structure
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.