Description

Benzenemethanesulfonyl Chloride, 4-Methoxy- is a specialized aromatic sulfonyl chloride derivative, a key building block in advanced organic synthesis. Its primary value lies in its reactivity as a sulfonylation agent, enabling the introduction of the methoxybenzenesulfonyl moiety to create novel compounds with tailored properties. This intermediate is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for developing active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A critical reagent in the synthesis of potential drug candidates, especially in creating sulfonamide-based molecules for various therapeutic areas.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides where the methoxybenzenesulfonyl group imparts specific biological activity.
• Material Science Research: Employed in the production of specialty polymers and advanced materials that require sulfonated aromatic structures.
• Chemical Biology & Proteomics: Acts as a versatile tool for modifying peptides, proteins, and other biomolecules to study function or create conjugates.
• Dye and Pigment Manufacturing: Serves as an intermediate in the synthesis of complex colorants and functional dyes.
• Cross-Coupling Reactions: Utilized in palladium-catalyzed reactions to construct complex biaryl systems important in medicinal chemistry.

Basic Information

Product Name	Benzenemethanesulfonyl Chloride, 4-Methoxy-
CAS No.	110661-59-1
Molecular Formula	C8H9ClO3S
Molecular Weight	220.67 g/mol
Synonyms	4-Methoxybenzenemethanesulfonyl Chloride; p-Methoxybenzenemethanesulfonyl Chloride; 4-Methoxybenzylsulfonyl Chloride; (4-Methoxyphenyl)methanesulfonyl Chloride; p-Methoxybenzylsulfonyl Chloride; 4-Methoxy-α-toluenesulfonyl Chloride; 1-(Chlorosulfonylmethyl)-4-methoxybenzene; 4-Methoxybenzyl Chlorosulfonate
EINECS	Contact for details

Quality Control

Our Benzenemethanesulfonyl Chloride, 4-Methoxy- is produced under stringent quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC for purity, NMR for structural confirmation, and Karl Fischer titration for moisture content, to ensure it meets the high standards required for research and industrial synthesis. A detailed Certificate of Analysis (COA) is provided with each shipment, guaranteeing traceability and consistent quality.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Melting Point	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.