Description

Psammaplin A is a potent and naturally occurring marine-derived metabolite with significant biological activity. This compound is valued for its role as a powerful inhibitor of histone deacetylases (HDACs) and DNA methyltransferases (DNMTs), making it a critical research tool in epigenetics and oncology. It is primarily utilized by pharmaceutical researchers, academic institutions, and biotechnology companies for drug discovery, biochemical pathway analysis, and the development of novel therapeutic agents targeting cancer and other diseases.

Application

• Epigenetics Research: As a dual inhibitor of HDAC and DNMT enzymes, it is a key compound for studying gene expression regulation, chromatin remodeling, and epigenetic modifications.
• Oncology and Cancer Drug Discovery: Used in preclinical research to investigate anti-proliferative and pro-apoptotic mechanisms in various cancer cell lines.
• Biochemical Assay Development: Serves as a reference standard and active control in high-throughput screening (HTS) assays for identifying new epigenetic modulators.
• Academic and Pharmaceutical R&D: Employed in fundamental research to understand the role of epigenetic dysregulation in disease pathology.
• Marine Natural Product Studies: Used as a reference compound in the chemical and pharmacological investigation of marine sponges and their metabolites.

Basic Information

Product Name	Psammaplin A
CAS No.	110659-91-1
Molecular Formula	C22H22Br2N4O6S2
Molecular Weight	678.37 g/mol
Synonyms	Psammaplin A; (E)-N,N'-(Disulfanediylbis(4,1-phenylene))bis(2-((3-(3,5-dibromo-4-hydroxyphenyl)acryloyl)amino)acetamide); Psammaplin A from Pseudoceratina purpurea; HDAC Inhibitor XI; DNMT/HDAC Dual Inhibitor
EINECS	Contact for details

Quality Control

Our Psammaplin A is produced and handled under strict quality management protocols to ensure batch-to-batch consistency and high purity for research applications. Each lot is accompanied by comprehensive analytical documentation, including HPLC chromatograms and NMR data. Certificates of Analysis (COA) detailing purity, identity, and strength are available upon request to support your regulatory and research needs.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store at -20°C or below under an inert atmosphere. Allow the product to equilibrate to room temperature in a desiccator before opening to prevent condensation and moisture uptake.

Specification

Item	Specification
Appearance	Off-white to light yellow solid
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 1.0%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.