Description

Forskolin, 7Beta-Deacetyl-7Beta-[γ-(Morpholino) Butyryl]-, Hydrochloride is a chemically modified derivative of forskolin, designed to enhance its pharmacological profile and stability for advanced research and development. This high-purity compound is critical for investigating intracellular signaling pathways, particularly those involving adenylate cyclase activation and cyclic AMP (cAMP) modulation. It is primarily utilized by pharmaceutical researchers, biochemical assay developers, and academic institutions focused on metabolic, cardiovascular, and neurological studies.

Application

• Biochemical Research: A key tool compound for studying cAMP-dependent signal transduction mechanisms in cell-based assays.
• Pharmaceutical Development: Serves as a reference standard and a potential intermediate or active pharmaceutical ingredient (API) in preclinical drug discovery programs.
• Enzyme Studies: Used to investigate the activation and inhibition profiles of adenylate cyclase isoforms.
• Metabolic Research: Applied in studies exploring lipolysis, insulin secretion, and other metabolic processes regulated by cAMP.
• Cardiovascular Research: Employed in models studying vasodilation, cardiac contractility, and blood pressure regulation.
• Neuroscience: Utilized in research on neurotransmitter release, synaptic plasticity, and neuroprotection.

Basic Information

Product Name	Forskolin, 7Beta-Deacetyl-7Beta-[γ-(Morpholino) Butyryl]-, Hydrochloride
CAS No.	110452-74-9
Molecular Formula	C29H42ClN2O6
Molecular Weight	549.11 g/mol
Synonyms	7-Deacetyl-7-[4-(morpholinyl)butyryl]forskolin hydrochloride; 7-Deacetyl-7-O-[4-(morpholino)butyryl]forskolin HCl; 7β-Deacetyl-7β-[γ-(morpholino)butyryl]forskolin hydrochloride; 1α,6β,9α-Trihydroxy-8,13-epoxy-labd-14-en-11-one, 7-Deacetyl-7-[4-(4-morpholinyl)-1-oxobutyl]-, Hydrochloride; Colforsin derivative; NKH 477 (analog); Colforsin daproate derivative hydrochloride
EINECS	Contact for details

Quality Control

Our Forskolin, 7Beta-Deacetyl-7Beta-[γ-(Morpholino) Butyryl]-, Hydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity, NMR and MS for structural confirmation, and comprehensive residual solvent analysis. Certificates of Analysis (COA) detailing all specifications are provided to ensure traceability and compliance with research-grade standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.