Description

5-Iodonaphthalene-1-Sulfonylchloride is a high-purity, reactive chemical intermediate primarily used in advanced organic synthesis. This compound is valued for its role as a versatile building block in the creation of complex molecules, particularly in pharmaceutical and materials science research. It is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries who require a reliable and high-quality sulfonylation reagent.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting specific enzyme inhibition or receptor binding.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and pesticides with enhanced efficacy and selectivity.
• Functional Material Synthesis: Serves as a building block for creating advanced organic electronic materials, dyes, and photoactive compounds.
• Bioconjugation & Labeling: Useful in the modification of biomolecules for analytical, diagnostic, or therapeutic purposes due to its reactive sulfonyl chloride group.
• Cross-Coupling Reactions: The iodine substituent makes it a valuable substrate for palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Sonogashira) to construct complex aromatic systems.
• Chemical Probe Development: Employed in medicinal chemistry to create activity-based probes for studying biological pathways and target identification.

Basic Information

Product Name	5-Iodonaphthalene-1-Sulfonylchloride
CAS No.	110448-35-6
Molecular Formula	C10H6ClIO2S
Molecular Weight	352.57 g/mol
Synonyms	1-Naphthalenesulfonyl chloride, 5-iodo-; 5-Iodo-1-naphthalenesulfonyl chloride; 5-Iodonaphthalene-1-sulfonyl chloride; 1-Naphthalenesulfonic acid, 5-iodo-, chloride; 5-Iodo-1-naphthalenesulphonyl chloride; 5-Iodonaphthalenesulfonyl chloride; 5-Iodo-1-naphthalenesulfonylchloride; 5-Iodo-1-naphthalenesulfonic acid chloride
EINECS	Contact for details

Quality Control

Our 5-Iodonaphthalene-1-Sulfonylchloride is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity. Each lot is analyzed using advanced techniques including HPLC, NMR, and IR spectroscopy. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept tightly sealed and stored in a dark location to maintain stability and purity.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.