Description

Benzyloxycarbonylalanyl-Alanyl-Prolyl-Valine-Trifluoromethyl Ketone is a synthetic, fluorinated peptide derivative designed as a potent and selective protease inhibitor. This compound is of significant value in biochemical research and pharmaceutical development for studying enzyme mechanisms and designing therapeutic agents. It is primarily needed by research institutions, pharmaceutical R&D departments, and biotechnology companies focused on protease-targeted drug discovery and biochemical pathway analysis.

Application

• Protease Inhibition Research: Serves as a key biochemical tool for investigating the activity and inhibition kinetics of specific serine or cysteine proteases.
• Drug Discovery & Development: Used as a lead compound or intermediate in the design and synthesis of novel therapeutic agents targeting proteolytic enzymes.
• Biochemical Assay Development: Employed as a standard or control in high-throughput screening (HTS) assays to identify new protease inhibitors.
• Mechanistic Studies: Facilitates the study of enzyme-substrate interactions and catalytic mechanisms due to its reactive trifluoromethyl ketone group.
• Academic Research: Utilized in university and institutional labs for fundamental research in enzymology, chemical biology, and medicinal chemistry.

Basic Information

Product Name	Benzyloxycarbonylalanyl-Alanyl-Prolyl-Valine-Trifluoromethyl Ketone
CAS No.	110407-54-0
Molecular Formula	C27H37F3N4O7
Molecular Weight	586.60 g/mol
Synonyms	Z-Ala-Ala-Pro-Val-CF3; Z-AAPV-CF3; Cbz-Ala-Ala-Pro-Val-Trifluoromethyl Ketone; Ala-Ala-Pro-Val-CF3 (Z-blocked); Benzyloxycarbonyl-Ala-Ala-Pro-Val-Trifluoromethylketone; Protease Inhibitor 110407-54-0; (2S)-1-[(2S)-2-[[(2S)-2-[[(2S)-2-[[(benzyloxy)carbonyl]amino]propanoyl]amino]propanoyl]amino]-3-methylbutanoyl]-N-[(3S)-1,1,1-trifluoro-4-oxopentan-3-yl]pyrrolidine-2-carboxamide
EINECS	Contact for details

Quality Control

Our Benzyloxycarbonylalanyl-Alanyl-Prolyl-Valine-Trifluoromethyl Ketone is manufactured under controlled conditions and undergoes rigorous analytical testing to ensure high purity and batch-to-batch consistency, suitable for research applications. Each batch is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to stringent in-house quality standards to support reliable and reproducible scientific results.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a freezer. Due to its hygroscopic (moisture-sensitive) nature, the container should be sealed under an inert atmosphere (e.g., nitrogen or argon) after each use and allowed to equilibrate to room temperature before opening to minimize moisture uptake.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (Mass Spec)	Conforms
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.