Description

Karwinskia Toxin T-514 is a potent phytotoxin isolated from plants of the genus *Karwinskia*, primarily used as a critical reference standard and research tool. This compound is essential for scientific investigations into its unique mechanism of action, which involves the selective inhibition of protein synthesis. It is primarily needed by researchers and laboratories in the fields of toxicology, pharmacology, and plant biochemistry for analytical studies, method development, and as a biological probe.

Application

• Analytical Reference Standard: Serves as a high-purity calibrant for the identification and quantification of T-514 toxin in complex matrices using techniques like HPLC and LC-MS.
• Toxicological Research: Used in in-vitro and in-vivo studies to investigate the biochemical pathways, cellular toxicity, and organ-specific effects of Karwinskia poisoning.
• Pharmacological Studies: Employed as a tool compound to study its mechanism of action on ribosomes and protein synthesis inhibition, aiding in fundamental biological research.
• Forensic Analysis: Critical for the development and validation of diagnostic assays to detect and confirm exposure to Karwinskia species in clinical and forensic settings.
• Plant Biochemistry Research: Used to study the biosynthesis, ecological role, and distribution of toxic compounds within the *Karwinskia* genus.
• Quality Control in Manufacturing: Acts as a system suitability standard for companies producing diagnostic kits or reagents related to plant toxin detection.

Basic Information

Product Name	Karwinskia Toxin T-514
CAS No.	110270-61-6
Molecular Formula	C29H34O10
Molecular Weight	542.58 g/mol
Synonyms	T-514; Toxin T-514; Karwinskia Toxin; Karwinskia humboldtiana Toxin T-514; 7-Hydroxy-6-methoxy-3-methyl-1,2,3,4,4a,10b-hexahydrobenzo[c]phenanthridine-1,4a-dicarboxylic acid dimethyl ester; Peroxisomicine A1; Contact for additional synonyms.
EINECS	Contact for details

Quality Control

Our Karwinskia Toxin T-514 is produced and handled under strict quality protocols to ensure identity, purity, and stability for research applications. Each batch is thoroughly characterized using advanced analytical techniques, including HPLC, NMR, and MS. A comprehensive Certificate of Analysis (COA) detailing purity, identification, and impurity profiles is provided with every shipment to support your research integrity and compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) or as indicated on the label or COA. This product is light-sensitive (store away from light) and hygroscopic (moisture-sensitive). Keep the container tightly sealed in a dry environment. For long-term storage, consider storing desiccated at -20°C.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.