Description

Glucose-13C6 is a stable isotope-labeled analog of D-glucose, where all six carbon atoms are the non-radioactive carbon-13 isotope. This high-purity compound is essential for advanced analytical and metabolic research, providing a critical internal standard for mass spectrometry and enabling precise tracking of glucose metabolism in complex biological systems. It is primarily utilized by research institutions, pharmaceutical developers, and diagnostic manufacturers in the fields of metabolomics, tracer studies, and clinical diagnostics.

Application

• Metabolomics & Flux Analysis: Used as a stable isotope tracer to map and quantify metabolic pathways in cells, tissues, and organisms.
• Mass Spectrometry (MS) Internal Standard: Serves as a critical reference standard for the accurate quantification of endogenous glucose in LC-MS and GC-MS applications.
• Pharmaceutical R&D: Employed in drug metabolism and pharmacokinetics (DMPK) studies to investigate the effects of new compounds on glucose utilization.
• Clinical Research: Facilitates studies on diabetes, insulin resistance, and other metabolic disorders by tracing glucose uptake and conversion.
• NMR Spectroscopy: Used in nuclear magnetic resonance studies for structural and dynamic analysis of metabolic processes.
• Biochemical Assay Development: Acts as a calibrated substrate in enzymatic assays and diagnostic kit manufacturing.

Basic Information

Product Name	Glucose-13C6
CAS No.	110187-42-3
Molecular Formula	¹³C₆H₁₂O₆
Molecular Weight	186.10 g/mol
Synonyms	D-Glucose-13C6; D-(+)-Glucose-13C6; Dextrose-13C6; ¹³C6-Glucose; D-Glucose (U-13C6); D-Glucose (13C6); (2R,3S,4R,5R)-2,3,4,5,6-Pentahydroxyhexanal-13C6; Isotopic Glucose; Stable Isotope Labeled Glucose
EINECS	Contact for details

Quality Control

Every batch of Glucose-13C6 is manufactured and tested under strict quality management systems to ensure exceptional isotopic and chemical purity. Our products undergo rigorous quality testing, including isotopic enrichment analysis by NMR and MS, to ensure compliance with research-grade standards. A comprehensive Certificate of Analysis (COA) detailing isotopic purity, chemical purity, and specific tests is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. This material is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccant or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Isotopic Purity (¹³C)	≥ 99 atom % ¹³C
Chemical Purity (HPLC)	≥ 98.0%
Specific Optical Rotation	+52.5° to +53.0° (c=10, H₂O)
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.