Description

11-Deoxy-13,14-Dihydro-15-Keto-11Beta,16Chi-Cycloprostaglandin E2 is a chemically modified prostaglandin E2 (PGE2) analog, a key intermediate in the synthesis of advanced pharmaceutical compounds. Its unique cyclopentane ring structure provides enhanced metabolic stability, making it a valuable tool for targeted drug discovery and development in the life sciences sector. This high-purity compound is essential for researchers and manufacturers in pharmaceutical R&D, particularly for developing novel therapeutics targeting inflammation, pain, and reproductive health.

Application

• Pharmaceutical Intermediate: Critical building block for synthesizing novel prostaglandin-based drugs with improved pharmacokinetic profiles.
• Biochemical Research: Used as a reference standard and probe in studies of prostaglandin receptors (EP receptors) and their signaling pathways.
• Drug Discovery: Serves as a key scaffold in medicinal chemistry for developing anti-inflammatory and analgesic agents.
• Academic Research: Employed in university and institutional labs for investigating the role of prostaglandins in physiological and pathological processes.
• Contract Manufacturing (CMO): Supplied to CMOs for the cGMP production of clinical trial materials and active pharmaceutical ingredients (APIs).
• Reference Material: Utilized in analytical method development and validation for quality control in pharmaceutical manufacturing.

Basic Information

Product Name	11-Deoxy-13,14-Dihydro-15-Keto-11Beta,16Chi-Cycloprostaglandin E2
CAS No.	109826-53-1
Molecular Formula	C₂₀H₃₀O₅
Molecular Weight	350.45 g/mol
Synonyms	11-Deoxy-13,14-dihydro-15-keto-11β,16ξ-cycloprostaglandin E2; 11-Deoxy-13,14-dihydro-15-keto-11β,16ε-cycloprostaglandin E2; Cycloprostaglandin E2 derivative; Modified PGE2 analog; 11β,16ξ-Cyclo-PGE2 derivative; Prostaglandin E2 cyclopentane analog; (5Z)-7-[(1R,2R,3R)-3-Hydroxy-2-[(1E,3S)-3-hydroxyoct-1-en-1-yl]-5-oxocyclopentyl]hept-5-enoic acid (related IUPAC form)
EINECS	Contact for details

Quality Control

Our 11-Deoxy-13,14-Dihydro-15-Keto-11Beta,16Chi-Cycloprostaglandin E2 is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and structural confirmation via NMR and Mass Spectrometry. We provide comprehensive Certificates of Analysis (COA) with detailed chromatographic data, ensuring traceability and compliance with research and development standards. Specifications can be tailored to meet specific project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under an inert atmosphere (e.g., argon or nitrogen) to prevent oxidation. The container should be kept in a dry, cool, and well-ventilated area. Allow the sealed container to reach room temperature before opening to minimize moisture condensation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.