Description

(3-Chloro-4-Fluorophenyl)Acetaldehyde is a versatile aromatic aldehyde building block, essential for advanced organic synthesis. Its molecular structure, featuring both chloro and fluoro substituents, makes it a critical intermediate for introducing specific electronic and steric properties into target molecules. This compound is primarily sought after by research and development chemists in the pharmaceutical and agrochemical industries for constructing complex active ingredients.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel active pharmaceutical ingredients (APIs), particularly in drug discovery programs targeting CNS disorders and metabolic diseases.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and insecticides, where the halogenated phenyl ring enhances biological activity and environmental stability.
• Liquid Crystal & OLED Materials: Serves as a precursor for synthesizing fluorinated and chlorinated aromatic cores used in electronic display materials and organic light-emitting diodes (OLEDs).
• Fine Chemical & Dye Intermediate: Employed in the manufacture of specialized dyes, pigments, and performance chemicals requiring halogenated aromatic aldehydes.
• Cross-Coupling Reactions: A valuable substrate in palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Heck) to create complex biaryl structures.
• Academic & Contract Research: Utilized in university and CRO laboratories for methodological development and the exploration of new synthetic pathways.

Basic Information

Item	Details
Product Name	(3-Chloro-4-Fluorophenyl)Acetaldehyde
CAS No.	109346-86-3
Molecular Formula	C8H6ClFO
Molecular Weight	172.58 g/mol
Synonyms	2-(3-Chloro-4-fluorophenyl)acetaldehyde; 3-Chloro-4-fluorobenzeneacetaldehyde; (3-Chloro-4-fluorophenyl)ethanal; 2-(3-Chloro-4-fluorophenyl)ethanal; 109346-86-3; NSC 405124; 3-Chloro-4-fluoro phenylethanal
EINECS	Contact for details

Quality Control

Every batch of (3-Chloro-4-Fluorophenyl)Acetaldehyde is produced under strict quality management protocols. We employ advanced analytical techniques, including GC, HPLC, and NMR, to ensure identity, purity, and consistency meet the high standards required for research and commercial synthesis. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). This product is easily oxidized and should be handled under an inert atmosphere for long-term storage. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC/HPLC)	≥ 97.0% (Area %)
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.