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2,4-Dichloro-Alpha,Alpha,Alpha,3-Tetrafluorotoluene, 1,3-Dichloro-2-Fluoro-4-(Trifluoromethyl)Benzene CAS NO 109292-70-8


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CAS No.:109292-70-8

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

2,4-Dichloro-Alpha,Alpha,Alpha,3-Tetrafluorotoluene, also known as 1,3-Dichloro-2-Fluoro-4-(Trifluoromethyl)Benzene, is a highly fluorinated and chlorinated aromatic building block of significant commercial importance. This compound is valued for its unique molecular structure, which imparts specific electronic and steric properties critical for advanced synthesis. It serves as a key intermediate in the development of pharmaceuticals, agrochemicals, and specialty materials, where its halogenated pattern enables precise molecular modifications.

Application

  • Pharmaceutical Intermediate: A critical building block in the synthesis of active pharmaceutical ingredients (APIs), particularly for molecules requiring fluorinated aromatic cores to modulate bioavailability and metabolic stability.
  • Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and insecticides, where the fluorine and chlorine substituents enhance biological activity and environmental persistence.
  • Liquid Crystal & OLED Materials: Serves as a precursor for fluorinated components in electronic display materials, contributing to improved dielectric anisotropy and thermal stability.
  • Polymer & Resin Modifier: Incorporated into specialty polymers to alter surface properties, increase chemical resistance, and improve weatherability.
  • Organic Synthesis Reagent: Employed in cross-coupling reactions and nucleophilic aromatic substitutions as a versatile, multi-halogenated substrate for complex molecule assembly.

Basic Information

Item Detail
Product Name 2,4-Dichloro-Alpha,Alpha,Alpha,3-Tetrafluorotoluene / 1,3-Dichloro-2-Fluoro-4-(Trifluoromethyl)Benzene
CAS No. 109292-70-8
Molecular Formula C7H2Cl2F4
Molecular Weight 232.99 g/mol
Synonyms 1,3-Dichloro-2-fluoro-4-(trifluoromethyl)benzene; 2,4-Dichloro-α,α,α,3-tetrafluorotoluene; 2-Fluoro-1,3-dichloro-4-(trifluoromethyl)benzene; 4-(Trifluoromethyl)-1,3-dichloro-2-fluorobenzene; Benzene, 1,3-dichloro-2-fluoro-4-(trifluoromethyl)-; 2,4-Dichloro-α,α,α,3-tetrafluoromethylbenzene
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Quality Control

Our production of 2,4-Dichloro-Alpha,Alpha,Alpha,3-Tetrafluorotoluene adheres to a stringent quality management system. Every batch undergoes comprehensive analytical testing, including GC, HPLC, and NMR, to ensure high purity and consistent lot-to-lot performance. We provide detailed Certificates of Analysis (COA) for traceability and support compliance with relevant regulatory frameworks for industrial and research use.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from strong bases and incompatible materials. Due to its fluoride/strong alkali chemical property, ensure storage areas are free from contamination.

Specification

Item Specification
Appearance Colorless to pale yellow liquid
Identification (IR) Conforms to structure
Assay (GC) ≥ 98.0%
Water Content (KF) ≤ 0.5%
Related Substances (GC) Individual impurity ≤ 1.0%; Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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