Description

N(Alpha)-(2-Naphthylsulfonylglycyl)-1-(4-Aminomethylphenylalanine)Piperidide is a specialized synthetic peptide derivative with a complex molecular architecture. This compound is valued for its role as a key intermediate or building block in advanced pharmaceutical research and development. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical and biotechnology industries for the synthesis of novel therapeutic agents, particularly in protease inhibitor and peptidomimetic drug discovery programs.

Application

• Pharmaceutical Intermediate: Serves as a critical building block in the synthesis of potential drug candidates, especially protease inhibitors.
• Peptidomimetic Research: Used in the design and development of peptide-like molecules that mimic natural peptides but with enhanced stability and bioavailability.
• Biochemical Tool Compound: Employed in enzymatic studies and as a reference standard in analytical method development for related compounds.
• Medicinal Chemistry: Utilized in structure-activity relationship (SAR) studies to optimize the potency and selectivity of lead molecules.
• Custom Synthesis: Acts as a starting material for the contract manufacturing of specialized APIs (Active Pharmaceutical Ingredients) for clinical trials.

Basic Information

Product Name	N(Alpha)-(2-Naphthylsulfonylglycyl)-1-(4-Aminomethylphenylalanine)Piperidide
CAS No.	108460-11-3
Molecular Formula	C31H34N4O5S
Molecular Weight	574.69 g/mol
Synonyms	Nα-(2-Naphthylsulfonylglycyl)-1-(4-aminomethylphenylalanine)piperidide; 1-[[(2-Naphthalenesulfonyl)glycyl]amino]-3-(4-aminomethylphenyl)-1-oxo-2-(1-piperidinyl)propane; (S)-1-((S)-2-((2-Naphthylsulfonyl)amino)acetamido)-3-(4-(aminomethyl)phenyl)-1-oxo-2-(piperidin-1-yl)propane; NSC 339586; Glycine, N-[(2-naphthalenylsulfonyl)-, (1S)-1-[[(1S)-3-[4-(aminomethyl)phenyl]-1-oxo-1-(1-piperidinyl)-2-propanyl]amino]carbonyl]methyl ester; Peptidomimetic building block 108460-11-3.
EINECS	Contact for details

Quality Control

Our N(Alpha)-(2-Naphthylsulfonylglycyl)-1-(4-Aminomethylphenylalanine)Piperidide is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for pharmaceutical research. Certificates of Analysis (COA) with detailed chromatographic data are provided with every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.