Description

Aurachin D is a specialized quinoline alkaloid compound of significant interest in biochemical and pharmacological research. Its primary value lies in its potent and specific inhibitory activity against the cytochrome bc1 complex (Complex III) in the mitochondrial electron transport chain. This makes it a critical research tool for scientists studying cellular respiration, bioenergetics, and the development of novel antimicrobial and antiparasitic agents. Key industries and applications include academic and pharmaceutical R&D, particularly in the fields of microbiology, parasitology, and mitochondrial biology.

Application

• Biochemical Research: As a specific inhibitor of the cytochrome bc1 complex (ubiquinol-cytochrome c reductase) for studying mitochondrial electron transport and oxidative phosphorylation.
• Antimicrobial Agent Development: Investigation of its mechanism of action against bacteria and fungi due to its disruption of energy metabolism.
• Antiparasitic Studies: Research into its efficacy against parasites like Plasmodium (malaria) and Toxoplasma gondii, which rely on similar electron transport chains.
• Mode-of-Action Studies: Used as a reference compound to elucidate the mechanisms of other respiratory chain inhibitors and to validate new drug targets.
• Enzyme Kinetics: Tool for kinetic analysis and characterization of the bc1 complex in purified enzyme preparations or mitochondrial membranes.
• Cell Biology: Probing the role of mitochondrial function in apoptosis, cell signaling, and metabolic diseases.

Basic Information

Product Name	Aurachin D
CAS No.	108354-13-8
Molecular Formula	C₂₅H₃₃NO₃
Molecular Weight	395.54 g/mol
Synonyms	2-Undec-10-enyl-3-methyl-4-quinolone; 2-(10-Undecenyl)-3-methyl-4(1H)-quinolinone; Aurachin D; Cytochrome bc1 Complex Inhibitor; Respiratory Chain Inhibitor; 3-Methyl-2-(10-undecenyl)-4-quinolone; 4-Quinolinone, 2-(10-undecenyl)-3-methyl-
EINECS	Contact for details

Quality Control

Every batch of Aurachin D is produced and analyzed under strict quality protocols to ensure identity, purity, and consistency for research applications. Our products undergo rigorous quality testing, including advanced chromatographic and spectroscopic methods, to ensure compliance with industry standards. A comprehensive Certificate of Analysis (COA) detailing purity, identity confirmation, and impurity profile is provided with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). This product is hygroscopic (moisture-sensitive); ensure the container is sealed tightly after each use to minimize exposure to atmospheric humidity. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	Yellow to light brown powder or crystalline solid
Identification (HPLC)	Retention time corresponds to reference standard
Identification (IR)	Spectrum matches reference
Purity (HPLC)	≥ 95% (Research Grade)
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.