Description

5-(Bromomethyl)-2-(Trifluoromethyl)Pyridine is a versatile and high-value halogenated pyridine derivative, serving as a critical building block in advanced organic synthesis. Its molecular structure, featuring both a reactive bromomethyl group and a stable trifluoromethyl moiety, makes it an essential intermediate for constructing complex molecules with tailored properties. This compound is primarily sought after by research institutions and manufacturers in the pharmaceutical, agrochemical, and material science sectors for developing new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders, inflammation, and oncology.
• Agrochemical Synthesis: Used to construct novel herbicides, fungicides, and insecticides, where the trifluoromethyl group enhances biological activity and metabolic stability.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands used in transition metal catalysis and asymmetric synthesis.
• Material Science Precursor: Employed in the development of advanced polymers, liquid crystals, and organic electronic materials due to its ability to modify electronic properties.
• Cross-Coupling Reactions: The bromomethyl group is an excellent handle for Suzuki, Stille, and other palladium-catalyzed cross-coupling reactions to form new carbon-carbon bonds.
• Fluorine Chemistry Research: A valuable compound for studying the influence of the trifluoromethyl group on physicochemical parameters like lipophilicity and metabolic profile.

Basic Information

Product Name	5-(Bromomethyl)-2-(Trifluoromethyl)Pyridine
CAS No.	108274-33-5
Molecular Formula	C7H5BrF3N
Molecular Weight	240.02 g/mol
Synonyms	2-(Trifluoromethyl)-5-(bromomethyl)pyridine; 5-Bromomethyl-2-trifluoromethylpyridine; 2-Trifluoromethyl-5-bromomethylpyridine; (6-Trifluoromethyl-3-pyridyl)methyl bromide; 3-Pyridinemethanol, 6-(trifluoromethyl)-, bromide; 108274-33-5; 5-Bromomethyl-2-(trifluoromethyl)pyridine
EINECS	Contact for details

Quality Control

Our 5-(Bromomethyl)-2-(Trifluoromethyl)Pyridine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure high purity and consistent performance. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing identity, assay, and impurity profiles. Our quality commitment aligns with cGMP principles for advanced intermediates, ensuring reliability for your critical synthesis workflows.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be amber-colored or stored in dark conditions.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.