Description

3-Fluoro-5-Nitrobenzaldehyde is a high-purity aromatic aldehyde building block characterized by its strategically positioned fluorine and nitro substituents. This compound is essential for advanced organic synthesis, where its reactive aldehyde group and electron-withdrawing substituents enable precise molecular construction. It is primarily utilized by research and development chemists and process engineers in the pharmaceutical, agrochemical, and specialty chemical industries for creating novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex drug molecules, particularly those targeting central nervous system (CNS) disorders and oncology.
• Agrochemical Synthesis: Used in the development of advanced herbicides, fungicides, and pesticides, leveraging the fluorine atom for enhanced bioactivity and metabolic stability.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands used in asymmetric catalysis and metal-organic frameworks (MOFs).
• Material Science Research: Employed in the synthesis of organic semiconductors, liquid crystals, and photoactive polymers due to its electron-deficient aromatic system.
• Chemical Biology Probes: Utilized to develop fluorescent tags and molecular probes for studying biological processes and enzyme activity.
• Custom Synthesis and Scale-up: A critical building block for contract research organizations (CROs) and custom manufacturers serving the life sciences sector.

Basic Information

Product Name	3-Fluoro-5-Nitrobenzaldehyde
CAS No.	108159-96-2
Molecular Formula	C7H4FNO3
Molecular Weight	169.11 g/mol
Synonyms	5-Nitro-3-fluorobenzaldehyde; 3-Fluoro-5-nitro-benzaldehyde; Benzaldehyde, 3-fluoro-5-nitro-; 3-Fluor-5-nitrobenzaldehyd; 3-Fluoro-5-nitrobenzenecarboxaldehyde
EINECS	Contact for details

Quality Control

Our 3-Fluoro-5-Nitrobenzaldehyde is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC for purity, GC for residual solvents, and NMR/IR for structural confirmation, to ensure it meets the stringent requirements of research and industrial synthesis. A detailed Certificate of Analysis (COA) is provided with each shipment, documenting all critical quality attributes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. This material is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	Yellow to pale yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	95 - 99 °C
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.