Description

Deoxygalactonojirimycin, Hydrochloride is a potent and selective glycosidase inhibitor, specifically targeting α-galactosidase. This compound is a critical research-grade biochemical for investigating lysosomal storage disorders, carbohydrate metabolism, and glycobiology pathways. It is essential for pharmaceutical R&D, academic research, and the development of therapeutic agents for conditions like Fabry disease.

Application

• Biochemical Research: A key tool for studying enzyme kinetics, inhibition mechanisms, and the role of glycosidases in cellular processes.
• Pharmaceutical Development: Serves as a reference standard and active pharmaceutical ingredient (API) intermediate in the research of treatments for lysosomal storage diseases.
• Glycobiology Studies: Used to probe complex carbohydrate synthesis and degradation pathways, aiding in the understanding of glycosylation disorders.
• Cell Biology: Employed in vitro to modulate glycosidase activity to study its effects on cell signaling, adhesion, and pathology.
• Diagnostic Reagent Manufacturing: Potential use in the formulation of enzyme assay kits and diagnostic reagents for genetic disorder screening.

Basic Information

Product Name	Deoxygalactonojirimycin, Hydrochloride
CAS No.	108147-54-2
Molecular Formula	C7H15NO4 • HCl
Molecular Weight	213.66 g/mol (Free base: 177.20)
Synonyms	1-Deoxygalactonojirimycin HCl; DGJ HCl; D-Galactostatin Hydrochloride; (2R,3R,4R,5S)-2-(Hydroxymethyl)piperidine-3,4,5-triol Hydrochloride; 1,5-Dideoxy-1,5-imino-D-galactitol Hydrochloride; α-Galactosidase Inhibitor; Migalastat Hydrochloride Impurity/Intermediate
EINECS	Contact for details

Quality Control

Our Deoxygalactonojirimycin, Hydrochloride is manufactured under strict quality systems. Each batch undergoes comprehensive analytical testing including HPLC for purity, NMR and IR for structural confirmation, and tests for residual solvents and heavy metals. A Certificate of Analysis (COA) detailing all specifications is provided to ensure traceability and compliance with research and development standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C. This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥98.0%
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm
Specific Rotation	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.