Description

Cytochalasino CAS NO 108050-26-6 is a potent and specific fungal metabolite belonging to the cytochalasin family, known for its ability to disrupt actin polymerization in eukaryotic cells. This compound is a critical research tool for studying cytoskeletal dynamics, cell motility, and cytokinesis. It is primarily utilized by life science researchers, pharmaceutical developers, and academic institutions engaged in cell biology and biochemical pathway analysis.

Application

• Cell Biology Research: Used as a cytoskeletal disruptor to inhibit actin filament polymerization, facilitating studies on cell shape, motility, and intracellular transport.
• Cancer Research: Employed to investigate the role of the actin cytoskeleton in tumor cell invasion, metastasis, and the mechanisms of cell division.
• Neuroscience Studies: Applied in research on neuronal growth cone dynamics, synaptic vesicle trafficking, and other actin-dependent processes in neurons.
• Developmental Biology: A key reagent for examining cytokinesis, embryogenesis, and morphogenetic movements that depend on actin filament assembly.
• Pharmaceutical Screening: Serves as a reference standard and a tool compound in high-throughput assays targeting the cytoskeleton for drug discovery.
• Microbiology: Used to study host-pathogen interactions, particularly how certain pathogens manipulate the host cell's actin network for internalization and movement.

Basic Information

Product Name	Cytochalasino
CAS No.	108050-26-6
Molecular Formula	C29H37NO5
Molecular Weight	479.61 g/mol
Synonyms	Cytochalasin O; Cytochalasin-O; 108050-26-6; NSC 357756; (3S,6S,7S,8R,16R)-6,7-Epoxy-16-hydroxy-4,4,8,14-tetramethyl-3-[(1E)-1-methyl-2-oxo-2-(1H-pyrrol-2-yl)ethylidene]-10-oxa-13-azabicyclo[10.3.1]hexadeca-1(15),12(16),13-triene-5,9,11-trione
EINECS	Contact for details

Quality Control

Our Cytochalasino is produced and handled under strict quality management protocols to ensure batch-to-batch consistency and high purity for research applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to relevant standards for research-grade biochemicals to support reproducible scientific results.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This product is hygroscopic (moisture-sensitive) and light-sensitive. Allow the vial to warm to room temperature in a desiccator before opening to minimize moisture uptake.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.