Description

(3R,4R)-3-Hydroxy-5-[(E)-1-Propenyl]Cyclo[L-Leu-L-Abu-Sar-n-Methyl-L-Leu-L-Val-n-Methyl-L-Leu-L-Ala-D-Ala-n-Methyl-L-Leu-n-Methyl-L-Leu-n-Methyl-L-Val-] is a complex, cyclic depsipeptide compound of significant interest in advanced pharmaceutical research and development. This molecule matters due to its intricate stereochemistry and potential as a key intermediate or pharmacophore for novel therapeutic agents. It is primarily needed by research institutions, pharmaceutical companies, and biotechnology firms engaged in the discovery and synthesis of new bioactive peptides and macrocyclic drugs.

Application

• Pharmaceutical Research & Development: As a sophisticated building block or reference standard in the discovery of new peptide-based therapeutics.
• Chemical Biology Studies: For investigating protein-protein interactions, enzyme inhibition, and cellular signaling pathways due to its macrocyclic structure.
• Advanced Intermediate Synthesis: Serving as a crucial precursor in the multi-step synthesis of complex natural product analogs or novel drug candidates.
• Analytical Reference Standard: Used in method development and validation for HPLC, LC-MS, or NMR analysis within quality control and research laboratories.

Basic Information

Product Name	(3R,4R)-3-Hydroxy-5-[(E)-1-Propenyl]Cyclo[L-Leu-L-Abu-Sar-n-Methyl-L-Leu-L-Val-n-Methyl-L-Leu-L-Ala-D-Ala-n-Methyl-L-Leu-n-Methyl-L-Leu-n-Methyl-L-Val-]
CAS No.	108027-39-0
Molecular Formula	C73H126N12O15
Molecular Weight	1387.85 g/mol
Synonyms	Cyclo[L-Leu-L-Abu-Sar-N-Me-L-Leu-L-Val-N-Me-L-Leu-L-Ala-D-Ala-N-Me-L-Leu-N-Me-L-Leu-N-Me-L-Val-(3R,4R)-3-Hydroxy-5-[(E)-1-Propenyl]]; Depsipeptide 108027-39-0; Cyclic Peptide 108027-39-0; (3R,4R)-3-Hydroxy-5-(1-Propenyl)-Cyclodepsipeptide; Macrocyclic Depsipeptide; [Abu2, Sar3, N-Me-Leu4,7,10,11, Val5, Ala8, D-Ala9, N-Me-Val12]-Cyclodepsipeptide Derivative
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards. Every batch is characterized using advanced analytical techniques including HPLC, MS, and NMR to confirm identity and purity. Certificates of Analysis (COA) detailing all relevant specifications are available upon request. We adhere to a quality management system suitable for supplying materials for research and development purposes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Residue on Ignition	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.