Description

Z-Phe-Phe-Fluoromethylketone is a potent and selective fluoromethyl ketone-based inhibitor, widely recognized for its role as a cysteine protease inhibitor. This compound is critical for researchers and developers in the life sciences sector, providing a key tool for studying enzyme mechanisms and developing therapeutic agents. It is primarily utilized by pharmaceutical R&D teams, biochemical researchers, and diagnostic manufacturers focused on protease-related pathways.

Application

• Biochemical Research: As a specific inhibitor for studying the activity and function of cysteine proteases like cathepsins.
• Pharmaceutical Development: A key intermediate or reference standard in the discovery of novel protease-targeting drugs for conditions such as osteoporosis, cancer, and inflammatory diseases.
• Enzyme Mechanism Studies: Used to elucidate catalytic mechanisms and inhibition kinetics in academic and industrial laboratories.
• Diagnostic Reagent Formulation: Employed in the development of assay kits and diagnostic tools that measure protease activity.
• Cell Biology & Immunology: Applied in research exploring the role of proteases in cellular processes, antigen presentation, and immune response.

Basic Information

Product Name	Z-Phe-Phe-Fluoromethylketone
CAS No.	108005-94-3
Molecular Formula	C26H25FN2O5
Molecular Weight	464.49 g/mol
Synonyms	Z-Phe-Phe-FMK; Z-Phe-Phe-CH2F; Benzyloxycarbonyl-Phe-Phe-fluoromethyl ketone; N-(Benzyloxycarbonyl)-L-phenylalanyl-L-phenylalanine fluoromethyl ketone; Cathepsin L Inhibitor I; Z-FF-FMK; Z-Phe-Phe-fluoromethane; Protease Inhibitor VI
EINECS	Contact for details

Quality Control

Our Z-Phe-Phe-Fluoromethylketone is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods. A Certificate of Analysis (COA) detailing all test results is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) in a dry environment. This material is hygroscopic (moisture-sensitive); ensure containers are sealed tightly after each use to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.