Description

Acetic-13C2-2-D3 Acid CAS NO 107745-70-0 is a high-purity, isotopically labeled derivative of acetic acid, specifically enriched with carbon-13 and deuterium. This compound is essential for advanced analytical research, serving as a critical internal standard and tracer in quantitative mass spectrometry and nuclear magnetic resonance (NMR) spectroscopy. It is primarily required by pharmaceutical R&D laboratories, metabolic research facilities, and agrochemical developers for precise drug metabolism and pharmacokinetics (DMPK) studies, environmental fate analysis, and complex metabolic pathway elucidation.

Application

• Quantitative Mass Spectrometry (MS): Used as a stable isotope-labeled internal standard for the accurate quantification of acetic acid and related metabolites in complex biological matrices.
• Nuclear Magnetic Resonance (NMR) Spectroscopy: Serves as a non-radioactive tracer for studying metabolic fluxes, enzymatic mechanisms, and reaction pathways in real-time.
• Pharmaceutical Research & DMPK Studies: Critical for tracking the absorption, distribution, metabolism, and excretion (ADME) of new drug candidates and their metabolites.
• Biochemical & Metabolic Research: Enables detailed investigation of central metabolic cycles like the citric acid (Krebs) cycle and fatty acid synthesis.
• Environmental Science: Applied in tracing the degradation pathways of organic compounds and studying biogeochemical cycles.
• Agrochemical Development: Utilized in mode-of-action studies and residue analysis of herbicides and pesticides.
• Diagnostic Assay Development: Employed in calibrating and validating clinical diagnostic tests for metabolic disorders.

Basic Information

Product Name	Acetic-13C2-2-D3 Acid
CAS No.	107745-70-0
Molecular Formula	13C2H2D3O2
Molecular Weight	64.07 g/mol (for 13C2H2D3O2)
Synonyms	Acetic-13C2-d3 Acid; [13C2,2,2,2-D3]Acetic Acid; Deuterated 13C-Acetic Acid; (13C2)Acetic-2,2,2-d3 Acid; Isotopic Acetic Acid; Ethanoic-13C2-2,2,2-D3 Acid; Glacial Acetic Acid-13C2-d3; Tracer Acetic Acid
EINECS	Contact for details

Quality Control

Every batch of Acetic-13C2-2-D3 Acid is manufactured and analyzed under strict quality protocols to ensure exceptional isotopic and chemical purity, critical for sensitive analytical applications. Our products undergo rigorous quality testing, including isotopic enrichment verification by NMR and MS, to ensure compliance with industry standards. Certificates of Analysis (COA) detailing batch-specific isotopic purity, chemical purity, and solvent residue are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, well-ventilated area at a controlled room temperature (15-25°C). Due to its highly volatile and strong acid/organic solvent nature, ensure containers are kept upright and away from heat sources, open flames, and incompatible materials such as strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	Clear, colorless liquid
Identification (IR)	Conforms to structure
Isotopic Purity (13C)	≥ 99 atom % 13C
Isotopic Purity (D)	≥ 98 atom % D
Chemical Purity (HPLC)	≥ 99.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.