Description

5-Fluoro-2-Picolinic Acid is a versatile fluorinated pyridine derivative that serves as a critical building block in advanced organic synthesis. Its unique structure, featuring both a carboxylic acid and a fluorine atom on the pyridine ring, makes it a valuable intermediate for creating complex molecules with tailored properties. This compound is essential for research and development in the pharmaceutical and agrochemical industries, where it is used to synthesize novel active ingredients. Its high purity and consistent quality are paramount for ensuring the success of downstream applications.

Application

• Pharmaceutical Intermediate: A key synthon in the development of active pharmaceutical ingredients (APIs), particularly for drugs targeting neurological disorders and oncology.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides, leveraging the fluorine atom for enhanced bioactivity and stability.
• Ligand in Catalysis: Serves as a precursor for creating specialized ligands used in transition metal-catalyzed cross-coupling reactions, such as Suzuki and Buchwald-Hartwig reactions.
• Material Science Research: Employed in the synthesis of functionalized polymers, metal-organic frameworks (MOFs), and other advanced materials with specific electronic or binding properties.
• Chemical Biology Probe Development: Utilized to create fluorinated probes and tags for studying biological processes and protein interactions.

Basic Information

Product Name	5-Fluoro-2-Picolinic Acid
CAS No.	107504-08-5
Molecular Formula	C6H4FNO2
Molecular Weight	141.10 g/mol
Synonyms	5-Fluoropyridine-2-carboxylic Acid; 2-Pyridinecarboxylic Acid, 5-Fluoro-; 5-Fluoro-2-pyridinecarboxylic Acid; 5-Fluoropicolinic Acid; 5-Fluoropyridine-2-carboxylate; 5-Fluoro-2-pyridylcarboxylic Acid; 5-Fluoro-2-carboxypyridine; 5-Fluoro-2-picolinate
EINECS	Contact for details

Quality Control

Our 5-Fluoro-2-Picolinic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via IR and NMR spectroscopy, to ensure it meets the high standards required for research and industrial synthesis. Certificates of Analysis (COA) detailing all specifications are provided with every shipment. We are committed to consistent quality and supply reliability for our global B2B partners.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from incompatible materials such as strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	185 - 190 °C
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.