Description

Methyl 5-Fluoropicolinate is a high-purity fluorinated heterocyclic building block essential for advanced organic synthesis. This compound serves as a critical intermediate in the development of active pharmaceutical ingredients (APIs) and agrochemicals, where its picolinate ester and fluorine substituent enable precise molecular modifications. It is primarily utilized by research institutions and industrial manufacturers in the pharmaceutical, agrochemical, and specialty chemical sectors seeking to incorporate fluorinated pyridine motifs into novel compounds.

Application

• Pharmaceutical Intermediate: A key synthon for the synthesis of fluorinated drug candidates, particularly in kinase inhibitor and central nervous system (CNS) active molecule research.
• Agrochemical Synthesis: Used in the development of next-generation herbicides and pesticides, leveraging the fluorine atom for enhanced bioactivity and environmental stability.
• Ligand and Catalyst Preparation: Serves as a precursor for creating specialized ligands in coordination chemistry and catalysis.
• Material Science Research: Employed in the synthesis of fluorinated organic materials and liquid crystals.
• Chemical Biology Probes: Useful for constructing fluorescent tags or molecular probes due to the modifiable ester functional group.
• Custom Synthesis and Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for bespoke synthesis projects.

Basic Information

Product Name	Methyl 5-Fluoropicolinate
CAS No.	107504-07-4
Molecular Formula	C7H6FNO2
Molecular Weight	155.13 g/mol
Synonyms	5-Fluoropyridine-2-carboxylic acid methyl ester; Methyl 5-fluoropyridine-2-carboxylate; 2-Pyridinecarboxylic acid, 5-fluoro-, methyl ester; 5-Fluoro-2-pyridinecarboxylic acid methyl ester; 5-Fluoropicolinic acid methyl ester; Methyl 5-fluoro-2-pyridinecarboxylate; 107504-07-4
EINECS	Contact for details

Quality Control

Our Methyl 5-Fluoropicolinate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide Certificates of Analysis (COA) with detailed specifications for every shipment, supporting your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. The container should be kept tightly sealed to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥98.0%
Related Substances (HPLC)	Total impurities ≤2.0%
Residual Solvents (GC)	Complies with ICH guidelines
Melting Point	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.