Description

Isoquinolin-6-Sulfonyl Chloride is a high-purity, reactive sulfonyl chloride derivative of isoquinoline, serving as a critical building block in advanced organic synthesis. Its primary value lies in its ability to act as a versatile sulfonylation reagent, facilitating the introduction of the isoquinoline-6-sulfonyl moiety into target molecules. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for the development of novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of potential drug candidates, especially enzyme inhibitors and receptor modulators.
• Agrochemical Research: Used in creating novel herbicides, fungicides, and insecticides with specific sulfonamide functionalities.
• Material Science: Employed in the development of specialty polymers, dyes, and photoactive materials.
• Chemical Biology: Acts as a probe or labeling reagent for studying protein interactions and enzyme activity.
• Custom Synthesis: Serves as a starting material for contract research organizations (CROs) and CDMOs for client-specific molecule development.

Basic Information

Product Name	Isoquinolin-6-Sulfonyl Chloride
CAS No.	107322-01-0
Molecular Formula	C9H6ClNO2S
Molecular Weight	227.67 g/mol
Synonyms	6-Isoquinolinesulfonyl chloride; Isoquinoline-6-sulfonyl chloride; 1-Isoquinolinesulfonyl chloride; 6-Chlorosulfonylisoquinoline; 107322-01-0; Isoquinoline-6-sulfonic acid chloride; 6-(Chlorosulfonyl)isoquinoline
EINECS	Contact for details

Quality Control

Our Isoquinolin-6-Sulfonyl Chloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via IR and NMR spectroscopy, to ensure it meets the high standards required for research and development. A detailed Certificate of Analysis (COA) is provided with every shipment, guaranteeing traceability and consistent quality.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) to prevent degradation. Keep away from strong acids and incompatible organic solvents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.