Description

1-Fluoropyridinium Tetrafluoroborate is a versatile fluorinating reagent and a key synthetic intermediate in advanced organic chemistry. Its primary value lies in its ability to introduce fluorine atoms or fluoropyridinium moieties into target molecules, enabling the development of novel pharmaceuticals and agrochemicals. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and materials science industries seeking to create new compounds with enhanced properties.

Application

• Pharmaceutical Intermediate: A critical building block for the synthesis of fluorinated active pharmaceutical ingredients (APIs), particularly in the development of kinase inhibitors and other targeted therapies.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and pesticides where the introduction of fluorine improves metabolic stability and bioactivity.
• Fluorination Reagent: Serves as a source of electrophilic fluorine or a fluoropyridinium group in nucleophilic substitution and other fluorination reactions.
• Material Science Research: Employed in the development of fluorinated liquid crystals, polymers, and electronic materials to modify dielectric properties and stability.
• Organic Synthesis: Acts as a versatile reagent for constructing complex heterocyclic systems and facilitating challenging functional group transformations in fine chemical production.
• Chemical Research & Development: A valuable tool for medicinal chemists and process chemists in lead optimization and route scouting for new chemical entities.

Basic Information

Product Name	1-Fluoropyridinium Tetrafluoroborate
CAS No.	107264-09-5
Molecular Formula	C5H5BF5N
Molecular Weight	184.91 g/mol
Synonyms	1-Fluoropyridinium Tetrafluoroborate; 1-Fluoropyridinium Tetrakis(fluoranyl)boranuide; N-Fluoropyridinium Tetrafluoroborate; Pyridinium, 1-fluoro-, tetrafluoroborate(1-); N-Fluoropyridinium Fluoborate; N-Fluoropyridinium BF4; 1-Fluoropyridinium BF4; Fluoropyridinium Tetrafluoroborate
EINECS	Contact for details

Quality Control

Our 1-Fluoropyridinium Tetrafluoroborate is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC for assay and purity, NMR for structural confirmation, and Karl Fischer titration for moisture content. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting compliance with our stringent specifications. We support cGMP manufacturing for pharmaceutical applications and can provide materials for research, development, and commercial-scale production.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (e.g., nitrogen or argon) in a desiccator to prevent decomposition. Keep away from incompatible materials such as strong bases and strong reducing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.