Description

1-Fluoropyridinium Triflate is a highly reactive fluorinating reagent and a versatile electrophilic fluorination agent. This compound matters for its ability to introduce fluorine atoms into complex organic molecules under mild conditions, a critical transformation in modern pharmaceutical and agrochemical development. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials industries for synthesizing novel fluorinated compounds.

Application

• Electrophilic Fluorination in API Synthesis: Key reagent for the late-stage fluorination of drug candidates to modulate metabolism, bioavailability, and binding affinity.
• Agrochemical Intermediate Production: Used in the synthesis of fluorinated pesticides and herbicides to enhance their environmental stability and efficacy.
• Radiochemistry & PET Tracer Development: Employed in the preparation of fluorine-18 labeled precursors for Positron Emission Tomography (PET) imaging agents.
• Liquid Crystal & Electronic Material Synthesis: Facilitates the creation of fluorinated organic semiconductors and liquid crystal molecules for display technologies.
• Academic & Contract Research: A valuable tool for methodology development in organic synthesis and fluorochemistry research.
• Fine Chemical Manufacturing: Used in the production of specialized fluorinated building blocks and intermediates for various high-value chemical streams.

Basic Information

Product Name	1-Fluoropyridinium Triflate
CAS No.	107263-95-6
Molecular Formula	C6H5F4NO3S
Molecular Weight	263.17 g/mol
Synonyms	1-Fluoropyridinium Trifluoromethanesulfonate; N-Fluoropyridinium Triflate; N-Fluoropyridinium Trifluoromethanesulfonate; 1-Fluoropyridinium Trifluoromethanesulphonate; NFPyT; Selectfluor® Related Reagent; Pyridine, 1-fluoro-, salt with trifluoromethanesulfonic acid (1:1)
EINECS	Contact for details

Quality Control

Our 1-Fluoropyridinium Triflate is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing to ensure high purity and consistent performance. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles by NMR, HPLC, and Karl Fischer titration is provided with every shipment to support your quality and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at 2-8°C. This product is hygroscopic (moisture-sensitive) and must be handled under an inert atmosphere (e.g., nitrogen or argon) to prevent decomposition.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.