Description

1,6,7,8-Indolizinetetrol, Octahydro-, (1S,6R,7R,8R,8Ar)- is a high-purity, stereochemically defined indolizine derivative with significant potential in advanced organic synthesis. This compound matters as a sophisticated chiral building block, enabling the construction of complex molecular architectures with precise stereocontrol. It is primarily needed by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and natural product analogs.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and development of new therapeutic agents, particularly in alkaloid synthesis.
• Agrochemical Research: Used in creating novel, stereospecific pesticide and herbicide candidates with potentially enhanced activity and selectivity.
• Asymmetric Catalysis Ligand Precursor: Serves as a starting material for the synthesis of complex, polyfunctional ligands used in enantioselective catalytic reactions.
• Natural Product Synthesis: A critical intermediate in the total synthesis of complex natural products containing the indolizidine or related polyhydroxylated alkaloid core structures.
• Chemical Biology Probe Development: Utilized to create molecular tools for studying biological pathways and enzyme interactions due to its defined stereochemistry and functional groups.
• Academic & Institutional Research: Employed in universities and research institutes for methodological development in organic chemistry and stereochemistry studies.

Basic Information

Product Name	1,6,7,8-Indolizinetetrol, Octahydro-, (1S,6R,7R,8R,8Ar)-
CAS No.	107244-34-8
Molecular Formula	C8H16O4
Molecular Weight	176.21 g/mol
Synonyms	(1S,6R,7R,8R,8aR)-Octahydro-1,6,7,8-indolizinetetrol; (1S,6R,7R,8R,8aR)-Octahydroindolizine-1,6,7,8-tetrol; 1,6,7,8-Tetrahydroxyoctahydroindolizine (stereoisomer); DMDP (2,5-Dideoxy-2,5-imino-D-mannitol) stereoisomer; Polyhydroxylated indolizidine alkaloid precursor; Chiral indolizinetetrol; Octahydroindolizine-1,6,7,8-tetrol
EINECS	Contact for details

Quality Control

Our 1,6,7,8-Indolizinetetrol, Octahydro-, (1S,6R,7R,8R,8Ar)- is produced under strict quality management protocols to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical characterization, including chiral purity verification, to meet the exacting standards of research and process chemistry. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to prevent moisture absorption, which may affect stability and handling properties. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% ee
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.