Description

Esperamicin X CAS NO 107175-47-3 is a potent enediyne antitumor antibiotic belonging to the esperamicin family, known for its highly efficient DNA-cleaving activity. This compound is a critical research tool and a lead structure in the development of novel anticancer therapeutics and antibody-drug conjugates (ADCs). It is primarily required by pharmaceutical R&D laboratories, biotechnology companies, and academic institutions focused on oncology, molecular biology, and targeted drug delivery systems.

Application

• Anticancer Drug Discovery: Serves as a potent cytotoxic warhead in the research and development of novel chemotherapeutic agents.
• Antibody-Drug Conjugate (ADC) Payload: Used as a highly active payload for constructing ADCs, enabling targeted delivery of cytotoxicity to cancer cells.
• Biochemical Research: Employed as a precise molecular tool to study DNA damage and repair mechanisms, apoptosis, and cell cycle arrest.
• Mechanism of Action Studies: Utilized in pharmacological research to investigate the enediyne-mediated DNA cleavage process and its biological consequences.
• Structure-Activity Relationship (SAR) Analysis: Acts as a core structure for synthetic modification to develop analogs with improved efficacy or reduced toxicity.

Basic Information

Product Name	Esperamicin X
CAS No.	107175-47-3
Molecular Formula	C59H84N4O21S2
Molecular Weight	1225.44 g/mol
Synonyms	Esperamicin X; Esperamicin X1; Antibiotic BMY-28166; BMY 28166; BMY-28166; Esperamicin A1 analog; Enediyne antibiotic BMY-28166; (1S,3R,4S,5R,7S,8R,10S,11R,12S,14R,15S,17R,18S,20R,21S,23R,24S,26R,27S,29R,30S,32R,33S,35R,36S,38R,39S,41R,42S,44R,45S,47R,48S,50R,51S,53R,54S,56R,57S,59R)-59-[(2R,3S,4S,5S,6R)-4-Acetamido-3,5-dihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-3,5,8,10,12,15,17,20,21,24,26,29,30,33,35,38,39,42,44,47,48,51,53,56,57-pentacosaol
EINECS	Contact for details

Quality Control

Our Esperamicin X is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the high standards required for pharmaceutical research. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting purity, potency, and other critical parameters.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store at -20°C or below under an inert atmosphere. Allow the product to equilibrate to room temperature in a desiccator before opening to prevent condensation. The container should be kept in a dry, well-ventilated area designated for research chemicals.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (MS)	Conforms to reference standard
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 3.0%
Residual Solvents (GC)	Meets ICH guidelines
Biological Activity (Cell-based assay)	Reported value provided

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.