Description

Saframycin Y2B-D CAS NO 107163-30-4 is a specialized member of the saframycin class of compounds, known for their complex pyrrolo[1,4]benzodiazepine (PBD) dimer structure. This compound is valued for its potent biological activity, making it a critical intermediate and reference standard in advanced pharmaceutical research and development. It is primarily utilized by research institutions and pharmaceutical companies focused on oncology and antibiotic discovery, where precise molecular tools are essential for mechanism-of-action studies and novel drug design.

Application

• Pharmaceutical Reference Standard: Serves as a high-purity analytical standard for quality control and method validation in the production of related active pharmaceutical ingredients (APIs).
• Oncology Research: Used as a key biochemical tool in cancer research to study DNA-interactive agents and their mechanisms of cytotoxicity.
• Antibiotic Development: Acts as a lead compound or intermediate in the synthesis and development of novel antimicrobial agents targeting resistant bacterial strains.
• Biochemical Assays: Employed in in vitro assays to evaluate biological activity, potency, and selectivity against specific cellular targets.
• Academic & Contract Research: Utilized in university laboratories and CROs (Contract Research Organizations) for fundamental chemical biology studies and hit-to-lead optimization programs.

Basic Information

Product Name	Saframycin Y2B-D
CAS No.	107163-30-4
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	Saframycin Y2B-D; Antibiotic Y2B-D; NSC 650426; Saframycin Y 2B-D; 107163-30-4; (1'S)-1'-[(10S,11S,11aS)-2,3,10,11-Tetrahydro-7-methoxy-10-methyl-5,11a-epoxy-11H-pyrrolo[2,1-c][1,4]benzodiazepin-11-yl]ethyl carbamate (related core structure)
EINECS	Contact for details

Quality Control

Our Saframycin Y2B-D is produced under strict quality management protocols to ensure batch-to-batch consistency and high purity suitable for research applications. Each lot is characterized using advanced analytical techniques including HPLC, MS, and NMR to confirm identity and purity. A comprehensive Certificate of Analysis (COA) detailing all test results is provided with every shipment to support your regulatory and research documentation needs.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store at -20°C or below under an inert atmosphere. The product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. Allow the container to reach room temperature before opening to minimize moisture condensation.

Specification

Item	Specification
Appearance	Yellow to brown powder
Identification (HPLC)	Conforms to reference standard
Identification (MS)	Conforms to reference standard
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.