Description

5-Amino-2-(Trifluoromethyl)Pyridine is a versatile pyridine derivative distinguished by its amino and trifluoromethyl functional groups. This compound is a critical building block in advanced organic synthesis, valued for its ability to impart unique electronic and steric properties to target molecules. It is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for the creation of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon for the development of active pharmaceutical ingredients (APIs), particularly in antiviral, anticancer, and central nervous system (CNS) drug candidates.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides, where the trifluoromethyl group enhances biological activity and metabolic stability.
• Ligand and Catalyst Development: Serves as a precursor for nitrogen-containing ligands in transition metal catalysis and organocatalysis.
• Material Science Research: Employed in the synthesis of functionalized polymers, liquid crystals, and organic electronic materials.
• Chemical Biology Probes: Utilized to create molecular probes for studying enzyme function and biological pathways.

Basic Information

Product Name	5-Amino-2-(Trifluoromethyl)Pyridine
CAS No.	106877-33-2
Molecular Formula	C6H5F3N2
Molecular Weight	162.11 g/mol
Synonyms	2-(Trifluoromethyl)pyridin-5-amine; 2-Trifluoromethyl-5-aminopyridine; 5-Amino-2-trifluoromethylpyridine; 5-Amino-α,α,α-trifluoro-2-picoline; 2-Pyridinamine, 5-(trifluoromethyl)-
EINECS	Contact for details

Quality Control

Our 5-Amino-2-(Trifluoromethyl)Pyridine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and GC-MS, to ensure high purity and consistency. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). This material is easily oxidized and should be handled under an inert atmosphere for long-term storage or when opening a new container. Keep away from incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.